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- Annika Öhrfelt
Annika Öhrfelt
Researcher
Department of Psychiatry and-
Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive
Individuals.
Annika Öhrfelt, Andréa Lessa Benedet, Nicholas J. Ashton, Hlin Kvartsberg, Manu Vandijck, Michael W Weiner, John Q Trojanowski, Leslie M Shaw, Henrik Zetterberg, Kaj Blennow
Neurology - 2023 -
Full-length and C-terminal neurogranin in Alzheimer's disease cerebrospinal fluid analyzed by novel ultrasensitive
immunoassays
Annika Öhrfelt, J. Dumurgier, Henrik Zetterberg, A. Vrillon, Nicholas J. Ashton, Hlin Kvartsberg, E. Bouaziz-Amar, J. Hugon, C. Paquet, Kaj Blennow
Alzheimers Research & Therapy - 2020 -
Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer's and Parkinson's
disease
Simon Sjödin, Gunnar Brinkmalm, Annika Öhrfelt, L. Parnetti, S. Paciotti, O. Hansson, J. Hardy, Kaj Blennow, Henrik Zetterberg, Ann Brinkmalm
Alzheimer's Research & Therapy - 2019 -
Mass Spectrometric Analysis of Lewy Body-Enriched alpha-Synuclein in Parkinson's
Disease
Payel Bhattacharjee, Annika Öhrfelt, T. Lashley, Kaj Blennow, Ann Brinkmalm, Henrik Zetterberg
Journal of Proteome Research - 2019 -
A Novel ELISA for the Measurement of Cerebrospinal Fluid SNAP-25 in Patients with Alzheimer's
Disease.
Annika Öhrfelt, Ann Brinkmalm, Julien Dumurgier, Henrik Zetterberg, Elodie Bouaziz-Amar, Jacques Hugon, Claire Paquet, Kaj Blennow
Neuroscience - 2019 -
Detection of α-Synuclein in Biological Samples Using Mass
Spectrometry
Ann Brinkmalm, Annika Öhrfelt, Payel Bhattacharjee, Henrik Zetterberg
Methods in molecular biology (Clifton, N.J.) - 2019 -
Expression and secretion of synaptic proteins during stem cell differentiation to cortical
neurons.
Faisal Hayat Nazir, Bruno Becker, Ann Brinkmalm, Kina Höglund, Åsa P Sandelius, Petra Bergström, Tugce Munise Satir, Annika Öhrfelt, Kaj Blennow, Lotta Agholme, Henrik Zetterberg
Neurochemistry international - 2018 -
Evolution of cerebrospinal fluid total α-synuclein in Parkinson's
disease.
Marthe Gurine Førland, Annika Öhrfelt, Ole-Bjørn Tysnes, Kaj Blennow, Henrik Zetterberg, Kenn Freddy Pedersen, Guido Alves, Johannes Lange
Parkinsonism & related disorders - 2018 -
Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian
Disorders.
Simon Sjödin, Oskar Hansson, Annika Öhrfelt Olsson, Gunnar Brinkmalm, Henrik Zetterberg, Ann Brinkmalm-Westman, Kaj Blennow
Proteomics. Clinical applications - 2017 -
Validation of a new assay for α-synuclein detection in cerebrospinal
fluid.
Marthe Gurine Førland, Annika Öhrfelt, Linn Silje Oftedal, Ole-Bjørn Tysnes, Jan Petter Larsen, Kaj Blennow, Henrik Zetterberg, Guido Alves, Johannes Lange
Clinical chemistry and laboratory medicine - 2017 -
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's
disease.
Amanda Heslegrave, Wendy Heywood, Ross Paterson, Nadia Magdalinou, Johan Svensson, Per Johansson, Annika Öhrfelt, Kaj Blennow, John Hardy, Jonathan Schott, Kevin Mills, Henrik Zetterberg
Molecular neurodegeneration - 2016 -
Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or
mitoxantrone.
Annika Öhrfelt, Markus Axelsson, Clas Malmeström, Lenka Novakova, Amanda Heslegrave, Kaj Blennow, Jan Lycke, Henrik Zetterberg
Multiple sclerosis (Houndmills, Basingstoke, England) - 2016 -
Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's
Disease.
Annika Öhrfelt, Per Johansson, Anders Wallin, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow, Johan Svensson
Dementia and geriatric cognitive disorders extra - 2016 -
CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and
meta-analysis.
Bob Olsson, Ronald Lautner, Ulf Andreasson, Annika Öhrfelt, Erik Portelius, Maria Bjerke, Mikko Hölttä, Christoffer Rosén, Caroline Olsson, Gabrielle Strobel, Elizabeth Wu, Kelly Dakin, Max Petzold, Kaj Blennow, Henrik Zetterberg
The Lancet. Neurology - 2016 -
Alzheimer's disease-subcortical vascular disease spectrum in a hospital-based setting: overview of results from the Gothenburg MCI and dementia
studies.
Anders Wallin, Arto Nordlund, Michael Jonsson, Kaj Blennow, Henrik Zetterberg, Annika Öhrfelt Olsson, Jacob Stålhammar, Marie Eckerström, Mårten Carlsson, Erik Olsson, Mattias Göthlin, Johan Svensson, Sindre Rolstad, Carl Eckerström, Maria Bjerke
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 2016 -
The Gothenburg MCI study: design and distribution of Alzheimer's disease and subcortical vascular disease diagnoses from baseline to 6-year
follow-up.
Anders Wallin, Arto Nordlund, Michael Jonsson, Karin Lind, Åke Edman, Mattias Göthlin, Jacob Stålhammar, Marie Eckerström, Silke Kern, Anne Börjesson-Hanson, Mårten Carlsson, Erik Olsson, Henrik Zetterberg, Kaj Blennow, Johan Svensson, Annika Öhrfelt Olsson, Maria Bjerke, Sindre Rolstad, Carl Eckerström
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 2016 -
The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's
disease
Annika Öhrfelt, Ann Brinkmalm-Westman, J. Dumurgier, Gunnar Brinkmalm, O. Hansson, Henrik Zetterberg, E. Bouaziz-Amar, J. Hugon, C. Paquet, Kaj Blennow
Alzheimers Research & Therapy - 2016 -
Longitudinal Measurements of Cerebrospinal Fluid Biomarkers in Parkinson's
Disease.
Sara Hall, Yulia Surova, Annika Öhrfelt, Kaj Blennow, Henrik Zetterberg, Oskar Hansson
Movement disorders : official journal of the Movement Disorder Society - 2016 -
Targeting LAMP2 in human cerebrospinal fluid with a combination of immunopurification and high resolution parallel reaction monitoring mass
spectrometry.
Simon Sjödin, Annika Öhrfelt, Gunnar Brinkmalm, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm-Westman
Clinical proteomics - 2016 -
Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's
disease.
Hlin Kvartsberg, Flora H Duits, Martin Ingelsson, Niels Andreasen, Annika Öhrfelt, Kerstin Andersson, Gunnar Brinkmalm, Lars Lannfelt, Lennart Minthon, Oskar Hansson, Ulf Andreasson, Charlotte E Teunissen, Philip Scheltens, Wiesje M van der Flier, Henrik Zetterberg, Erik Portelius, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2015 -
CSF biomarkers and clinical progression of Parkinson
disease.
Sara Hall, Yulia Surova, Annika Öhrfelt, Henrik Zetterberg, Daniel Lindqvist, Oskar Hansson
Neurology - 2015 -
Cerebrospinal Fluid Patterns and the Risk of Future Dementia in Early, Incident Parkinson
Disease.
David C Bäckström, Magdalena Eriksson Domellöf, Jan Linder, Bob Olsson, Annika Öhrfelt, Miles Trupp, Henrik Zetterberg, Kaj Blennow, Lars Forsgren
JAMA NEUROLOGY - 2015 -
Explorative and targeted neuroproteomics in Alzheimer's
disease.
Ann Brinkmalm-Westman, Erik Portelius, Annika Öhrfelt, Gunnar Brinkmalm, Ulf Andreasson, Johan Gobom, Kaj Blennow, Henrik Zetterberg
Biochimica et biophysica acta - 2015 -
SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's
disease.
Ann Brinkmalm-Westman, Gunnar Brinkmalm, William G Honer, Lutz Frölich, Lucrezia Hausner, Lennart Minthon, Oskar Hansson, Anders Wallin, Henrik Zetterberg, Kaj Blennow, Annika Öhrfelt
Molecular neurodegeneration - 2014 -
Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to Alzheimer's
disease.
Oskar Hansson, Sara Hall, Annika Öhrfelt Olsson, Henrik Zetterberg, Kaj Blennow, Lennart Minthon, Katarina Nägga, Elisabet Londos, Shiji Varghese, Nour K Majbour, Abdulmonem Al-Hayani, Omar MA El-Agnaf
Alzheimer's research & therapy - 2014 -
Metabolite and Peptide Levels in Plasma and CSF Differentiating Healthy Controls from Patients with Newly Diagnosed Parkinson's
Disease.
Miles Trupp, Pär Jonsson, Annika Öhrfelt, Henrik Zetterberg, Ogonna Obudulu, Linus Malm, Anna Wuolikainen, Jan Linder, Thomas Moritz, Kaj Blennow, Henrik Antti, Lars Forsgren
Journal of Parkinson's disease - 2014 -
Targeting synaptic pathology with a novel affinity mass spectrometry
approach.
Ann Brinkmalm-Westman, Gunnar Brinkmalm, William G Honer, Julie A Moreno, Joel Jakobsson, Giovanna R Mallucci, Henrik Zetterberg, Kaj Blennow, Annika Öhrfelt
Molecular & cellular proteomics : MCP - 2014 -
Evaluation of the Cerebrospinal Fluid Amyloid-β1-42/Amyloid-β1-40 Ratio Measured by Alpha-LISA to Distinguish Alzheimer's Disease from Other Dementia
Disorders.
Magdalena Nutu, Henrik Zetterberg, Elisabet Londos, Lennart Minthon, Katarina Nägga, Kaj Blennow, Oskar Hansson, Annika Öhrfelt
Dementia and geriatric cognitive disorders - 2013 -
Soluble amyloid precursor protein α and β in CSF in Alzheimer's
disease.
Gunnar Brinkmalm, Ann Brinkmalm-Westman, Philippe Bourgeois, Rita Persson, Oskar Hansson, Erik Portelius, Marc Mercken, Ulf Andreasson, Stéphane Parent, Francesco Lipari, Annika Öhrfelt, Maria Bjerke, Lennart Minthon, Henrik Zetterberg, Kaj Blennow, Magdalena Nutu
Brain research - 2013 -
Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian
disorders.
Sara Hall, Annika Öhrfelt, Radu Constantinescu, Ulf Andreasson, Yulia Surova, Frederick Bostrom, Widner Håkan, Hilde Decraemer, Katarina Någga, Lennart Minthon, Elisabet Londos, Eugeen Vanmechelen, Björn Holmberg, Henrik Zetterberg, Kaj Blennow, Oskar Hansson, Christer Nilsson
Archives of neurology - 2012 -
An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal
fluid.
Gunnar Brinkmalm, Erik Portelius, Annika Öhrfelt, Niklas Mattsson, Rita Persson, Mikael K Gustavsson, Charles H Vite, Johan Gobom, Jan-Eric Månsson, Jonas Nilsson, Adnan Halim, Göran Larson, Ulla Rüetschi, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm-Westman
Journal of mass spectrometry : JMS - 2012 -
Characteristic clinical presentation and CSF biomarker pattern in cerebral small vessel
disease
Anders Wallin, Annika Öhrfelt Olsson, Maria Bjerke
Journal of the Neurological Sciences - 2012 -
Identification of Novel α-Synuclein Isoforms in Human Brain Tissue by using an Online NanoLC-ESI-FTICR-MS
Method.
Annika Öhrfelt Olsson, Henrik Zetterberg, Rita Persson, Dzemila Secic, Gunnar Brinkmalm, Anders Wallin, Ezra Mulugeta, Paul T Francis, Eugeen Vanmechelen, Dag Aarsland, Clive Ballard, Kaj Blennow, Ann Brinkmalm-Westman
Neurochemical research - 2011 -
Screening for new biomarkers for subcortical vascular dementia and Alzheimer's
disease
Annika Öhrfelt Olsson, Ulf Andreasson, Adam Simon, Henrik Zetterberg, Åke Edman, William Potter, Daniel Holder, Viswanath Devanarayan, Jeffrey Seeburger, David A Smith, Kaj Blennow, Anders Wallin
Dementia and Geriatric Cognitive Disorders Extra - 2011 -
Identification of novel N-terminal fragments of amyloid precursor protein in cerebrospinal
fluid.
Erik Portelius, Gunnar Brinkmalm, Ai Jun Tran, Ulf Andreasson, Henrik Zetterberg, Ann Brinkmalm-Westman, Kaj Blennow, Annika Öhrfelt Olsson
Experimental neurology - 2010 -
Transient inflammation in neurogenic regions after irradiation of the developing
brain.
Marie Kalm, Aya Fukuda, Hirotsugu Fukuda, Annika Öhrfelt Olsson, Birgitta Lannering, Thomas Björk-Eriksson, Kaj Blennow, Ildiko Marky, Klas Blomgren
Radiation research - 2009 -
Expression of Pisum sativum SAD polypeptides in production hosts and in planta: Tetrameric organization of the
protein
Nikolai Scherbak, Mikael Brosché, Anneli Ala-Haivala, Hija Strid, Annika Öhrfelt Olsson, Fredrik Nilsson, Ake Strid
PROTEIN EXPRESSION AND PURIFICATION - 2009 -
Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse
loss?
Annika Öhrfelt Olsson, Pierre Grognet, Niels Andreasen, Anders Wallin, Eugeen Vanmechelen, Kaj Blennow, Henrik Zetterberg
Neuroscience letters - 2009 -
Initial CSF total tau correlates with 1-year outcome in patients with traumatic brain
injury
Martin Öst, Karin Nylén, Ludvig Z Csajbok, Annika Öhrfelt Olsson, Mats Tullberg, Carsten Wikkelsö, Per Nellgård, Lars Rosengren, Kaj Blennow, Bengt Nellgård
Neurology - 2006 -
Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy
bodies.
Hugo Vanderstichele, Karen De Vreese, Kaj Blennow, Niels Andreasen, Christian Sindic, Adrian Ivanoiu, Harald Hampel, Katharina Bürger, Lucilla Parnetti, Alessia Lanari, Allesandro Padovani, Monica DiLuca, Miriam Bläser, Annika Öhrfelt Olsson, Hans Pottel, Frank Hulstaert, Eugeen Vanmechelen
Clinical chemistry and laboratory medicine : CCLM / FESCC - 2006