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- Xinxin Hao
Xinxin Hao
Research Assistant
Department of Microbiology and Immunology-
Truncating the spliceosomal 'rope protein' Prp45 results in Htz1 dependent
phenotypes.
Kateřina Abrhámová, Martina Groušlová, Anna Valentová, Xinxin Hao, Beidong Liu, Martin Převorovský, Ondřej Gahura, František Půta, Per Sunnerhagen, Petr Folk
RNA Biology - 2024 -
Elimination of virus-like particles reduces protein aggregation and extends replicative lifespan in Saccharomyces
cerevisiae
Kara Schneider, Xinxin Hao, Katharina Keuenhof, Lisa Larsson-Berglund, Artur Fischbach, Doryaneh Ahmadpour, Srishti Chawla, P. Gómez, Johanna L Höög, Per O Widlund, Thomas Nyström
Proceedings of the National Academy of Science of the United States of America - 2024 -
Nuclear Hsp104 safeguards the dormant translation machinery during
quiescence
Verena Kohler, Andreas Kohler, Lisa Larsson Berglund, Xinxin Hao, Sarah Gersing, Axel Imhof, Thomas Nyström, Johanna L Höög, Martin Ott, Claes Andreasson, Sabrina Buttner
NATURE COMMUNICATIONS - 2024 -
The yeast guanine nucleotide exchange factor Sec7 is a bottleneck in spatial protein quality control and detoxifies neurological disease
proteins
Roja Babazadeh, Kara Schneider, Artur Fischbach, Xinxin Hao, Bo Liu, Thomas Nyström
Scientific Reports - 2023 -
Calmodulin regulates protease versus co-chaperone activity of a
metacaspase
Anna Maria Eisele-Bürger, Frederik Eisele, Sandra Malmgren Hill, Xinxin Hao, Kara Schneider, Rahmi Imamoglu, David Balchin, Beidong Liu, F. Ulrich Hartl, Peter V. Bozhkov, Thomas Nyström
Cell Reports - 2023 -
The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces
cerevisiae
Rebecca Josefson, Navinder Kumar, Xinxin Hao, Beidong Liu, Thomas Nyström
Scientific Reports - 2023 -
Artificial Hsp104-mediated systems for re-localizing protein
aggregates
Artur Fischbach, Angela Johns, Kara Schneider, Xinxin Hao, P. Tessarz, Thomas Nyström
Nature Communications - 2023 -
Lsm7 phase-separated condensates trigger stress granule
formation
Michelle Lindström, Lihua Chen, Shan Jiang, Dan Zhang, Yuan Gao, J. Zheng, Xinxin Hao, Xiaoxue Yang, Arpitha Kabbinale, Johannes Thoma, Lisa Metzger, D. Y. Zhang, Xuefeng Zhu, H. S. Liu, Claes M Gustafsson, Björn Marcus Burmann, J. Winderickx, Per Sunnerhagen, Beidong Liu
Nature Communications - 2022 -
An Hsp90 co-chaperone links protein folding and degradation and is part of a conserved protein quality
control
Frederik Eisele, Anna Maria Eisele-Bürger, Xinxin Hao, Lisa Larsson Berglund, Johanna L Höög, Beidong Liu, Thomas Nyström
Cell Reports - 2021 -
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and
toxicity.
Stefanie Andersson, Antonia Romero, Joana Isabel Rodrigues, Sansan Hua, Xinxin Hao, Therese Jacobson, Vivien Karl, Nathalie Becker, Arghavan Ashouri, Sebastien Rauch, Thomas Nyström, Beidong Liu, Markus J. Tamás
Journal of cell science - 2021 -
FMN reduces Amyloid-beta toxicity in yeast by regulating redox status and cellular
metabolism
X. Chen, B. Y. Ji, Xinxin Hao, X. W. Li, Frederik Eisele, Thomas Nyström, D. Petranovic
Nature Communications - 2020 -
Yeast mismatch repair components are required for stable inheritance of gene
silencing
Qian Liu, Xuefeng Zhu, Michelle Lindström, Yonghong Shi, Ju Zheng, Xinxin Hao, Claes M Gustafsson, Beidong Liu
Plos Genetics - 2020 -
Syntaxin 5 Is Required for the Formation and Clearance of Protein Inclusions during Proteostatic
Stress
Roja Babazadeh, Doryaneh Ahmadpour, S. Jia, Xinxin Hao, Per O Widlund, Kara Schneider, Frederik Eisele, L. D. Edo, G. J. Smits, Beidong Liu, Thomas Nyström
Cell Reports - 2019 -
Loss of transcriptional control affects As(III)-induced protein
aggregation
Joana Isabel Rodrigues, Stefanie Andersson, Sansan Hua, Xinxin Hao, Therese Jacobson, Vivien Karl, Arghavan Ashouri, Thomas Nyström, Beidong Liu, Markus J. Tamás
Gordon Research Conference on Stress Proteins in Growth, Development & Disease 2019, Lucca, Italy - 2019 -
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and
toxicity
Stefanie Andersson, Joana Isabel Rodrigues, Antonia Romero, Sansan Hua, Xinxin Hao, Therese Jacobson, Vivien Karl, Arghavan Ashouri, José García-Martínez, José Enrique Pérez-Ortín3 Pérez-Ortín, Thomas Nyström, Beidong Liu, Markus J. Tamás
International Conference on Yeast Genetics and Molecular Biology, Gothenburg, Sweden, workshop presentation (2019) - 2019 -
Role of the ribosomal quality control machinery in nucleocytoplasmic translocation of polyQ-expanded huntingtin
exon-1
Ju Zheng, Junsheng Yang, Y. J. Choe, Xinxin Hao, Xiuling Cao, Q. Zhao, Y. J. Zhang, V. Franssens, F. U. Hartl, Thomas Nyström, J. Winderickx, Beidong Liu
Biochemical and Biophysical Research Communications - 2017 -
Differential effects of soluble and aggregating polyQ proteins on cytotoxicity and type-1 myosin-dependent endocytosis in
yeast
Lisa Larsson Berglund, Xinxin Hao, Beidong Liu, Julie Grantham, Thomas Nyström
Scientific Reports - 2017 -
Spatial sequestration and detoxification of Huntingtin by the ribosome quality control
complex
Junsheng Yang, Xinxin Hao, Xiuling Cao, Beidong Liu, Thomas Nyström
Elife - 2016 -
Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar
Functions
Sandra Malmgren Hill, Xinxin Hao, Johan Grönvall, Stephanie Spikings-Nordby, Per O Widlund, T. Amen, Anna Jorhov, Rebecca Josefson, D. Kaganovich, Beidong Liu, Thomas Nyström
Cell Reports - 2016 -
Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein
Aggregates
J. Song, Q. Yang, Junsheng Yang, Lisa C Larsson, Xinxin Hao, Xuefeng Zhu, Sandra Malmgren Hill, Marija Cvijovic, Julia Fernandez-Rodriguez, Julie Grantham, Claes M Gustafsson, Beidong Liu, Thomas Nyström
PLoS Genetics - 2014 -
Stress granule-defective mutants deregulate stress responsive
transcripts
Xiaoxue Yang, Yi Shen, Elena Garre, Xinxin Hao, Daniel Krumlinde, Marija Cvijovic, Christina Arens, Thomas Nyström, Beidong Liu, Per Sunnerhagen
PLoS Genetics - 2014 -
Life-span extension by a metacaspase in the yeast Saccharomyces
cerevisiae
Sandra Malmgren Hill, Xinxin Hao, Beidong Liu, Thomas Nyström
Science - 2014 -
Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent
silencing.
Antonio Caballero, Ana Ugidos, Beidong Liu, David Öling, Kristian Kvint, Xinxin Hao, Cora Mignat, Laurence Nachin, Mikael Molin, Thomas Nyström
Molecular cell - 2011 -
Segregation of protein aggregates involves actin and the polarity
machinery.
Beidong Liu, Lisa C Larsson, Vanessa Franssens, Xinxin Hao, Sandra Malmgren Hill, Veronica Andersson, Daniel Höglund, Jia Song, Xiaoxue Yang, David Öling, Julie Grantham, Joris Winderickx, Thomas Nyström
Cell - 2011 -
The Polarisome Is Required for Segregation and Retrograde Transport of Protein
Aggregates
Beidong Liu, Lisa C Larsson, Antonio Caballero, Xinxin Hao, David Öling, Julie Grantham, Thomas Nyström
Cell - 2010