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Jane Synnergren
Visiting Professor
Department of Molecular and Clinical Medicine-
Latent space arithmetic on data embeddings from healthy multi-tissue human RNA-seq decodes disease
modules
Hendrik A. De, Dimitri Guala, Mika Gustafsson, Jane Synnergren, Jesper Tegne, Zelmina Lubovac-Pilav, Rasmus Magnusson
PATTERNS - 2024 -
Enhancing Maturation and Translatability of Human Pluripotent Stem Cell-Derived Cardiomyocytes through a Novel Medium Containing Acetyl-CoA Carboxylase 2
Inhibitor
Claudia Correia, Jonas Christoffersson, Sandra Tejedor, Said El-Haou, Meztli Matadamas-Guzman, Syam Nair, Pierre Donnes, Gentian Musa, Mattias Rohman, Monika Sundqvist, Rebecca B. Riddle, Bramasta Nugraha, Ioritz Sorzabal Bellido, Markus Johansson, Qing-Dong Wang, Alejandro Hidalgo, Karin Jennbacken, Jane Synnergren, Daniela Spater
CELLS - 2024 -
Domain Generalization of Deep Learning Models Under Subgroup Shift in Breast Cancer
Prognosis
Sören Richard Stahlschmidt, Benjamin Ulfenborg, Göran Falkman, Jane Synnergren
21st IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2024 - 2024 -
Head-to-head comparison of relevant cell sources of small extracellular vesicles for cardiac repair: Superiority of embryonic stem
cells
Hernan Gonzalez-King, Patricia G. Rodrigues, Tamsin Albery, Benyapa Tangruksa, Ramya Gurrapu, Andreia M. Silva, Gentian Musa, Dominika Kardasz, Kai Liu, Bengt Kull, Karin Avall, Katarina Ryden-Markinhuhta, Tania Incitti, Nitin Sharma, Cecilia Graneli, Hadi Valadi, Kasparas Petkevicius, Miguel Carracedo, Sandra Tejedor, Alena Ivanova, Sepideh Heydarkhan-Hagvall, Phillipe Menasche, Jane Synnergren, Niek Dekker, Qing-Dong Wang, Karin Jennbacken
JOURNAL OF EXTRACELLULAR VESICLES - 2024 -
The Combination of Vascular Endothelial Growth Factor A (VEGF-A) and Fibroblast Growth Factor 1 (FGF1) Modified mRNA Improves Wound Healing in Diabetic Mice: An Ex Vivo and In Vivo
Investigation
Sandra Tejedor, Maria Wagberg, Claudia Correia, Karin Avall, Mikko Holtta, Leif Hultin, Michael Lerche, Nigel Davies, Nils Bergenhem, Arjan Snijder, Tom Marlow, Pierre Donnes, Regina Fritsche-Danielson, Jane Synnergren, Karin Jennbacken, Kenny Hansson
CELLS - 2024 -
Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and
therapeutics
Zahra Payandeh, Benyapa Tangruksa, Jane Synnergren, Sepideh Heydarkhan-Hagvall, Joel Z. Nordin, Samir EL. Andaloussi, Jan Borén, John Wiseman, Mohammad Bohlooly-Y, Lennart Lindfors, Hadi Valadi
MOLECULAR ASPECTS OF MEDICINE - 2024 -
Proteome of Personalized Tissue-Engineered
Veins
Susanna Larsson, Sandra Holmgren, Lachmi Jenndahl, Benjamin Ulfenborg, Raimund Strehl, Jane Synnergren, Nidal Ghosheh
ACS Omega - 2024 -
Predicting Cancer Stage from Circulating microRNA: A Comparative Analysis of Machine Learning
Algorithms
Sören Richard Stahlschmidt, Benjamin Ulfenborg, Jane Synnergren
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) - 2023 -
Expression of Stem Cell Niche-Related Biomarkers at the Base of the Human Tricuspid
Valve
Jacob Sjölin, Marianne Jonsson, Charlotta Orback, Anders Oldfors, Anders Jeppsson, Jane Synnergren, Victoria Rotter Sopasakis, Kristina Vukusic
Stem Cells and Development - 2023 -
Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional
Extensions
Muhammad Nawaz, Sepideh Heydarkhan-Hagvall, Benyapa Tangruksa, Hernán González-King Garibotti, Yujia Jing, Maugeri Marco, Franziska Kohl, Leif Hultin, Azadeh Reyahi, Alessandro Camponeschi, Bengt Kull, Jonas Christoffersson, Ola Grimsholm, Karin Jennbacken, Martina Sundqvist, John Wiseman, Abdel Wahad Bidar, Lennart Lindfors, Jane Synnergren, Hadi Valadi
Advanced Science - 2023 -
Regional transcriptomic profiling reveals immune system enrichment in nonfailing atria and all chambers of the failing human
heart
Mikael Sandstedt, Kristina Vukusic, Markus Johansson, Marianne Jonsson, Rasmus Magnusson, Lillemor Mattsson Hultén, Göran Dellgren, Anders Jeppsson, Anders Lindahl, Jane Synnergren, Joakim Sandstedt
American journal of physiology. Heart and circulatory physiology - 2023 -
Artificial Intelligence Supports Automated Characterization of Differentiated Human Pluripotent Stem
Cells
K. Marzec-Schmidt, N. Ghosheh, S. R. Stahlschmidt, B. Kuppers-Munther, Jane Synnergren, B. Ulfenborg
Stem Cells - 2023 -
Personalized tissue-engineered veins - long term safety, functionality and cellular transcriptome analysis in large
animals
Klas Österberg, Y. Bogestal, L. Jenndahl, T. Gustafsson-Hedberg, Jane Synnergren, G. Holmgren, E. Bom, S. Petronis, A. Krona, J. S. Eriksson, J. Rosendahl, V. Crisostomo, F. M. Sanchez-Margallo, C. Baez-Diaz, R. Strehl, Joakim Håkansson
Biomaterials Science - 2023 -
Human Pluripotent Stem Cell-Derived Hepatocytes Show Higher Transcriptional Correlation with Adult Liver Tissue than with Fetal Liver
Tissue.
Nidal Ghosheh, Barbara Küppers-Munther, Annika Asplund, Christian X Andersson, Petter Björquist, Tommy B Andersson, Helena Carén, Stina Simonsson, Peter Sartipy, Jane Synnergren
ACS omega - 2020 -
Barrier Properties and Transcriptome Expression in Human iPSC-Derived Models of the Blood-Brain
Barrier.
Louise Delsing, Pierre Dönnes, José Sánchez, Maryam Clausen, Dimitrios Voulgaris, Anna Falk, Anna Herland, Gabriella Brolén, Henrik Zetterberg, Ryan Hicks, Jane Synnergren
Stem cells (Dayton, Ohio) - 2018 -
Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic
Models
Anders Lundin, Louise Delsing, Maryam Clausen, Piero Ricchiuto, José Sanchez, Alan Sabirsh, Mei Ding, Jane Synnergren, Henrik Zetterberg, Gabriella Brolén, Ryan Hicks, Anna Herland, Anna Falk
Stem cell reports - 2018 -
Towards Creating the Perfect in Vitro Cell
Model
Malin K B Jonsson, Toon A B Van Veen, Jane Synnergren, Bruno Becker
Stem Cells International - 2016 -
Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem
cells.
Gustav Holmgren, Jane Synnergren, Yalda Rahpeymai Bogestål, Caroline Améen, Karolina Åkesson, Sandra Holmgren, Anders Lindahl, Peter Sartipy
Toxicology - 2015 -
Clinical Outcome 3 Years After Autologous Chondrocyte Implantation Does Not Correlate With the Expression of a Predefined Gene Marker Set in Chondrocytes Prior to Implantation but Is Associated With Critical Signaling
Pathways
Johan Stenberg, Tommy S. de Windt, Jane Synnergren, Lars Hynsjö, Josefine Van Der Lee, Daniel B.F. Saris, Mats Brittberg, Lars Peterson, Anders Lindahl
The Orthopaedic Journal of Sports Medicine - 2014 -
Long-Term Chronic Toxicity Testing Using Human Pluripotent Stem Cell-Derived
Hepatocytes
Gustav Holmgren, Anna-Karin Sjögren, I. Barragan, A. Sabirsh, Jane Synnergren, P. Bjorquist, M. Ingelman-Sundberg, B Tommy Andersson, Josefina Edsbagge
Drug Metabolism and Disposition - 2014 -
Comparison of human cardiac gene expression profiles in paired samples of right atrium and left ventricle collected in
vivo
Julia Asp, Jane Synnergren, Marianne Jonsson, Göran Dellgren, Anders Jeppsson
Physiological genomics - 2012 -
Expression of microRNAs and their target mRNAs in human stem cell-derived cardiomyocyte clusters and in heart
tissue.
Jane Synnergren, Caroline Améen, Anders Lindahl, Björn Olsson, Peter Sartipy
Physiological genomics - 2011 -
Human embryonic mesodermal progenitors highly resemble human mesenchymal stem cells and display high potential for tissue engineering
applications.
Giuseppe Maria de Peppo, Sara Svensson, Maria Lennerås, Jane Synnergren, Johan Stenberg, Raimund Strehl, Johan Hyllner, Peter Thomsen, Camilla Karlsson
Tissue engineering. Part A - 2010 -
Transcriptional profiling of human embryonic stem cells and their functional
derivatives
Jane Synnergren
2010 -
Transcriptional profiling of human embryonic stem cells differentiating to definitive and primitive endoderm and further toward the hepatic
lineage.
Jane Synnergren, Nico Heins, Gabriella Brolén, Gustav Eriksson, Anders Lindahl, Johan Hyllner, Björn Olsson, Peter Sartipy, Petter Björquist
Stem cells and development - 2010 -
Cardiomyogenic gene expression profiling of differentiating human embryonic stem
cells.
Jane Synnergren, Sudeshna Adak, Mikael C. O. Englund, Theresa L Giesler, Karin Noaksson, Anders Lindahl, Patric Nilsson, Deirdre Nelson, Stewart Abbot, Bj?rn Olsson, Peter Sartipy
Journal of biotechnology - 2008 -
Molecular signature of cardiomyocyte clusters derived from human embryonic stem
cells.
Jane Synnergren, Karolina Akesson, Kerstin Dahlenborg, Hilmar Vidarsson, Caroline Améen, Daniella Steel, Anders Lindahl, Björn Olsson, Peter Sartipy
Stem cells (Dayton, Ohio) - 2008 -
Differentiating human embryonic stem cells express a unique housekeeping gene
signature.
Jane Synnergren, Theresa L Giesler, Sudeshna Adak, Reeti Tandon, Karin Noaksson, Anders Lindahl, Patric Nilsson, Deirdre Nelson, Björn Olsson, Mikael C. O. Englund, Peter Sartipy, Stewart Abbot
Stem cells (Dayton, Ohio) - 2007