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- Philipp Klahn
Philipp Klahn
Senior Lecturer
Department of Chemistry & Molecular Biology-
Comprehensive Cell Biological Investigation of Cytochalasin B Derivatives with Distinct Activities on the Actin
Network
Mervic D. Dongock Kagho, Katharina Schmidt, Christopher Lambert, Thomas Kaufmann, Lili Jia, Jan Faix, Klemens Rottner, Marc Stadler, Theresia Stradal, Philipp Klahn
JOURNAL OF NATURAL PRODUCTS - 2024 -
Biocatalytic Ether Lipid Synthesis by an Archaeal
Glycerolprenylase
Felix Kaspar, Lea Eilert, Sophie Staar, Sangwar Wadtey Oung, Mario Wolter, Charity Ganskow, Sebastian Kemper, Philipp Klahn, Christoph R. Jacob, Wulf Blankenfeldt, Anett Schallmey
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION - 2024 -
Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1
Inhibitors
L. A. Jian, R. Zscherp, U. Beutling, X. F. Shen, S. Y. Xu, X. Zhang, M. Bronstrup, Philipp Klahn, Q. X. Sun
Journal of Medicinal Chemistry - 2023 -
Functional connectivity alterations of the somatomotor network in euthymic bipolar
disorder
Luisa Klahn, William Hedley Thompson, Christoph Abé, Benny Liberg, Carl Sellgren, Philipp Klahn, Mikael Landén
Neuroscience Applied - 2023 -
Design of non-cytotoxic 6,7-dihydroxycoumarin-5-carboxylates with antibiofilm activity against Staphylococcus aureus and Candida
albicans
R. Zscherp, Aishi Chakrabarti, A. P. Lehmann, H. Schrey, H. X. Zeng, W. Collisi, Philipp Klahn
Organic & Biomolecular Chemistry - 2023 -
Artificial Fluorescent Glucosinolates (F-GSLs) Are Transported by the Glucosinolate Transporters
GTR1/2/3
C. Kanstrup, C. C. Jimidar, J. Tomas, G. Cutolo, C. Crocoll, M. Schuler, Philipp Klahn, A. Tatibouet, H. H. Nour-Eldin
International Journal of Molecular Sciences - 2023 -
Biotransformation-coupled mutasynthesis for the generation of novel pristinamycin derivatives by engineering the phenylglycine
residue
O. Hennrich, L. Weinmann, A. Kulik, K. Harms, Philipp Klahn, J. W. Youn, F. Surup, Y. Mast
Rsc Chemical Biology - 2023 -
Synthesis of an Antimicrobial Enterobactin-Muraymycin Conjugate for Improved Activity Against Gram-Negative
Bacteria
C. Rohrbacher, R. Zscherp, S. C. Weck, Philipp Klahn, C. Ducho
Chemistry-a European Journal - 2023 -
Masked Amino Trimethyl Lock (H2N-TML) Systems: New Molecular Entities for the Development of Turn-On Fluorophores and Their Application in Hydrogen Sulfide (H2S) Imaging in Human
Cells
Claire Cheyenne Jimidar, Jörg Grunenberg, Bianka Karge, Hazel Leanne Sarah Fuchs, Mark Brönstrup, Philipp Klahn
Chemistry - A European Journal - 2022 -
Testing of Diamond Electrodes as Biosensor for Antibody-Based Detection of Immunoglobulin Protein with Electrochemical Impedance
Spectroscopy
M. Menzler, Charity Ganskow, M. Ruschig, E. Moustafa, V. Sittinger, K. Lachmann, E. V. Wenzel, G. Russo, Philipp Klahn, J. Gabler
C-Journal of Carbon Research - 2022 -
Alternative Assay Reagents for UV-Spectroscopic Detection of (Pyro-)Phosphate with the PUB
Module
F. Kaspar, Charity Ganskow, L. Eilert, Philipp Klahn, A. Schallmey
Analytical Chemistry - 2022 -
Advances in the Synthesis of Enterobactin, Artificial Analogues, and Enterobactin-Derived Antimicrobial Drug Conjugates and Imaging Tools for Infection
Diagnosis
Philipp Klahn, R. Zscherp, C. C. Jimidar
Synthesis-Stuttgart - 2022 -
Total Synthesis via Biomimetic Late-Stage Heterocyclization: Assignment of the Relative Configuration and Biological Evaluation of the Nitraria Alkaloid
(±)-Nitrabirine
Mervic D. Kagho, Helen Hintersatz, Andreas Ihle, Haoxuan Zeng, Hedda Schrey, Wera Colisi, Philipp Klahn, Marc Stadler, Clemens Bruhn, Tobias Rüffer, Heinrich Lang, Klaus Banert
Journal of Organic Chemistry - 2021 -
Biomimetic enterobactin analogue mediates iron-uptake and cargo transport intoE. coliandP.
aeruginosa
Robert Zscherp, Janetta Coetzee, Johannes Vornweg, Jörg Grunenberg, Jennifer Herrmann, Rolf Müller, Philipp Klahn
Chemical Science - 2021 -
Labyrinthopeptins exert broad-spectrum antiviral activity through lipid-binding-mediated
virolysis
Hans Prochnow, Katharina Rox, N. V. Suryanarayana Birudukota, Loreen Weichert, Sven Kevin Hotop, Philipp Klahn, Kathrin Mohr, Sergej Franz, Dominic H. Banda, Sebastian Blockus, Janine Schreiber, Sibylle Haid, Merel Oeyen, Javier P. Martinez, Roderich D. Süssmuth, Joachim Wink, Andreas Meyerhans, Christine Goffinet, Martin Messerle, Thomas F. Schulz, Andrea Kröger, Dominique Schols, Thomas Pietschmann, Mark Brönstrup
Journal of Virology - 2020 -
Cannabinoids-promising antimicrobial drugs or intoxicants with
benefits?
Philipp Klahn
Antibiotics - 2020 -
The nuclear export inhibitor aminoratjadone is a potent effector in extracellular-targeted drug
conjugates
Philipp Klahn, Verena Fetz, Antje Ritter, Wera Collisi, Bettina Hinkelmann, Tatjana Arnold, Werner Tegge, Katharina Rox, Stephan Hüttel, Kathrin I. Mohr, Joachim Wink, Marc Stadler, Josef Wissing, Lothar Jänsch, Mark Brönstrup
Chemical Science - 2019 -
Synthesis and Biochemical Evaluation of an Artificial, Fluorescent Glucosinolate
(GSL)
Carina Patrizia Glindemann, Anita Backenköhler, Matthias Strieker, Ute Wittstock, Philipp Klahn
ChemBioChem - 2019 -
Trimethyl Lock: A Multifunctional Molecular Tool for Drug Delivery, Cellular Imaging, and Stimuli-Responsive
Materials
Okoh Adeyi Okoh, Philipp Klahn
ChemBioChem - 2018 -
New structural templates for clinically validated and novel targets in antimicrobial drug research and
development
Philipp Klahn, Mark Brönstrup
Current Topics in Microbiology and Immunology - 2016 -
Abscisic acid: A phytohormone and mammalian cytokine as novel pharmacon with potential for future development into clinical
applications
Priya Sakthivel, Niharika Sharma, Philipp Klahn, Marcus Gereke, Dunja Bruder
Current Medicinal Chemistry - 2016 -
Total Synthesis and Biological Evaluation of Natural and Designed
Tubulysins
K. C. Nicolaou, Jun Yin, Debashis Mandal, Rohan D. Erande, Philipp Klahn, Michael Jin, Monette Aujay, Joseph Sandoval, Julia Gavrilyuk, Dionisios Vourloumis
Journal of the American Chemical Society - 2016 -
Gold(I)-catalyzed heterocyclization of β-alkynyl hydroxamic acids: Synthesis of
isoxazolidin-3-ones
Andreas P. Häring, Philipp Klahn, Martin Jübermann, Fabian Mohr, Stefan F. Kirsch
Monatshefte fur Chemie - 2015 -
The synthesis of α-azidoesters and geminal
triazides
Philipp Klahn, Hellmuth Erhardt, Andreas Kotthaus, Stefan F. Kirsch
Angewandte Chemie - International Edition - 2014 -
IBX-mediated dehydrogenation of substituted
β-oxonitriles
Philipp Klahn, Stefan F. Kirsch
European Journal of Organic Chemistry - 2014 -
Total synthesis of
(+)-cyperolone
Philipp Klahn, Alexander Duschek, Clémence Liébert, Stefan F. Kirsch
Organic Letters - 2012 -
Practical azidation of
1,3-dicarbonyls
Tobias Harschneck, Sara Hummel, Stefan F. Kirsch, Philipp Klahn
Chemistry - A European Journal - 2012 -
Electronic Fine-Tuning of Carbene Ligands and its Impact on Gold
Catalysis
Philipp Klahn, Stefan F. Kirsch
ChemCatChem - 2011 -
The use of COP-OAc in the catalyst-controlled syntheses of
1,3-polyols
Stefan F. Kirsch, Philipp Klahn, Helge Menz
Synthesis - 2011 -
Thienopyrimidines as β3-adrenoceptor agonists: Hit-to-lead
optimization
Stefan Tasler, Roland Baumgartner, Astrid Ammendola, Josef Schachtner, Tanja Wieber, Marcus Blisse, Sandra Rath, Mirko Zaja, Philipp Klahn, Udo Quotschalla, Peter Ney
Bioorganic and Medicinal Chemistry Letters - 2010 -
Gold-catalyzed reactivity of 3-silyloxy-1,5-enynes: a synthetic tool for the synthesis of complex structures and its
limitations
Helge Menz, Jörg T. Binder, Benedikt Crone, Alexander Duschek, Timm T. Haug, Stefan F. Kirsch, Philipp Klahn, Clémence Liébert
Tetrahedron - 2009