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- Johan Bylund
Johan Bylund
Professor
Odontology Section 3-
Low CD4 + T cell count is related to specific anti-nuclear antibodies, IFNα protein positivity and disease activity in systemic lupus erythematosus
pregnancy.
Agnes Torell, Marit Stockfelt, Kaj Blennow, Henrik Zetterberg, Tansim Akhter, Dag Leonard, Lars Rönnblom, Sofia Pihl, Muna Saleh, Christopher Sjöwall, Helena Strevens, Andreas Jönsen, Anders A Bengtsson, Estelle Trysberg, Maria Majczuk Sennström, Agneta Zickert, Elisabet Svenungsson, Iva Gunnarsson, Johan Bylund, Bo Jacobsson, Anna Rudin, Anna-Carin Lundell
Arthritis research & therapy - 2024 -
High levels of short chain fatty acids secreted by Candida albicans hyphae induce neutrophil chemotaxis via Free Fatty Acid Receptor
2.
Arsham Khamzeh, Agnes Dahlstrand Rudin, Vignesh Venkatakrishnan, Marios Stylianou, Felix Peter Sanchez Klose, Constantin F Urban, Halla Björnsdottir, Johan Bylund, Karin Christenson
Journal of leukocyte biology - 2024 -
The Pseudomonas aeruginosa lectin LecB modulates intracellular reactive oxygen species production in human
neutrophils
F. P. S. Klose, Agnes Dahlstrand Rudin, Linda Bergqvist, Julia Scheffler, Katarina Jönsson, Ulrika Islander, Anna Karlsson-Bengtsson, Johan Bylund, V. Venkatakrishnan
European Journal of Immunology - 2024 -
Glycoproteome remodeling and organelle-specific N-glycosylation accompany neutrophil
granulopoiesis.
Rebeca Kawahara, Julian Ugonotti, Sayantani Chatterjee, Harry C Tjondro, Ian Loke, Benjamin L Parker, Vignesh Venkatakrishnan, Regis Dieckmann, Zeynep Sumer-Bayraktar, Anna Karlsson-Bengtsson, Johan Bylund, Morten Thaysen-Andersen
Proceedings of the National Academy of Sciences of the United States of America - 2023 -
Protein N-glycosylation in the bronchoalveolar space differs between never-smokers and long-term smokers with and without
COPD.
Vignesh Venkatakrishnan, Kristina A Thomsson, Médea Padra, Anders Andersson, Bettina Brundin, Karin Christenson, Johan Bylund, Niclas G. Karlsson, Anders Lindén, Sara K. Lindén
Glycobiology - 2023 -
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via
candidalysin
L. Unger, S. Skoluda, E. Backman, B. Amulic, F. M. Ponce-Garcia, C. N. Etiaba, S. Yellagunda, R. Krüger, H. von Bernuth, Johan Bylund, B. Hube, J. R. Naglik, C. F. Urban
Embo Reports - 2023 -
Low-density granulocytes are related to shorter pregnancy duration but not to interferon alpha protein blood levels in systemic lupus
erythematosus.
Agnes Torell, Marit Stockfelt, Gunilla Larsson, Kaj Blennow, Henrik Zetterberg, Dag Leonard, Lars Rönnblom, Muna Saleh, Christopher Sjöwall, Helena Strevens, Andreas Jönsen, Anders A Bengtsson, Estelle Trysberg, Maria Majcuk Sennström, Agneta Zickert, Elisabet Svenungsson, Iva Gunnarsson, Karin Christenson, Johan Bylund, Bo Jacobsson, Anna Rudin, Anna-Carin Lundell
Arthritis research & therapy - 2023 -
Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human
neutrophils.
Vignesh Venkatakrishnan, Jonas Elmwall, Trisha Lahiri, Martina Sundqvist, Linda Bergqvist, Hakon Leffler, Ulf J Nilsson, Amanda Welin, Johan Bylund, Anna Karlsson-Bengtsson
Glycobiology - 2023 -
Severe chronic non-bacterial osteomyelitis in combination with total MPO deficiency and responsiveness to TNFα
inhibition
Martina Sundqvist, Karin Christenson, Per Wekell, Halla Björnsdottir, Agnes Dahlstrand Rudin, Felix Peter Sanchez Klose, Tilmann Kallinich, Amanda Welin, Lena Björkman, Johan Bylund, Anna Karlsson, Stefan Berg
Frontiers in Immunology - 2023 -
Antieosinophil Antibodies Alone or in Combination with Antineutrophil Cytoplasmic Antibodies (ANCA) Detected in Different Autoimmune
Conditions
Regis Dieckmann, Rille Pullerits, Johan Bylund, Anna Karlsson-Bengtsson, Hans Herlitz, Christine Wennerås, Pontus Thulin
Journal of Immunology Research - 2023 -
Systemic Galectin-3 in Smokers with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis: The Impact of
Exacerbations
Martina Sundqvist, Kristina Andelid, Ann Ekberg-Jansson, Johan Bylund, Anna Karlsson-Bengtsson, A. Linden
International Journal of Chronic Obstructive Pulmonary Disease - 2021 -
A rare CTSC mutation in Papillon-Lefèvre Syndrome results in abolished serine protease activity and reduced NET formation but otherwise normal neutrophil
function.
Felix Peter Sanchez Klose, Halla Björnsdottir, Agnes Dahlstrand Rudin, Tishana Persson, Arsham Khamzeh, Martina Sundqvist, Sara Thorbert-Mros, Regis Dieckmann, Karin Christenson, Johan Bylund
PloS one - 2021 -
Activated low-density granulocytes in peripheral and intervillous blood and neutrophil inflammation in placentas from SLE
pregnancies.
Marit Stockfelt, Gunilla Larsson, Hanna Engström, Henri Puttonen, Henrik Zetterberg, Kaj Blennow, Christopher Sjöwall, Helena Strevens, Andreas Jönsen, Anders A Bengtsson, Maria Majczuk Sennström, Agneta Zickert, Elisabet Svenungsson, Iva Gunnarsson, Estelle Trysberg, Bo Jacobsson, Anna-Karin Hultgård Ekwall, Karin Christenson, Johan Bylund, Mattias N D Svensson, Anna-Carin Lundell
Lupus science & medicine - 2021 -
Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty
Acids.
Agnes Dahlstrand Rudin, Arsham Khamzeh, Vignesh Venkatakrishnan, Tishana Persson, Michael Gabl, Otto Savolainen, Huamei Forsman, Claes Dahlgren, Karin Christenson, Johan Bylund
Frontiers in cellular and infection microbiology - 2021 -
The neutrophil subset defined by CD177 expression is preferentially recruited to gingival crevicular fluid in
periodontitis.
Agnes Dahlstrand Rudin, Firoozeh Amirbeagi, Lisa Davidsson, Arsham Khamzeh, Sara Thorbert Mros, Pontus Thulin, Amanda Welin, Lena Björkman, Karin Christenson, Johan Bylund
Journal of leukocyte biology - 2021 -
Short chain fatty acids released by Fusobacterium nucleatum are neutrophil chemoattractants acting via free fatty acid receptor 2
(FFAR2)
Agnes Dahlstrand Rudin, Arsham Khamzeh, Vignesh Venkatakrishnan, Amina Basic, Karin Christenson, Johan Bylund
Cellular Microbiology - 2021 -
Hyper-truncated Asn355- and Asn391-glycans modulate the activity of neutrophil granule
myeloperoxidase.
Harry C Tjondro, Julian Ugonotti, Rebeca Kawahara, Sayantani Chatterjee, Ian Loke, Siyun Chen, Fabian Soltermann, Hannes Hinneburg, Benjamin L Parker, Vignesh Venkatakrishnan, Regis Dieckmann, Oliver C Grant, Johan Bylund, Alison Rodger, Robert J Woods, Anna Karlsson-Bengtsson, Weston B Struwe, Morten Thaysen-Andersen
The Journal of biological chemistry - 2021 -
The secretion of cytokines by peripheral blood mononuclear cells of patients with periodontitis and healthy controls when exposed to
H2S
Amina Basic, G. Serino, Åsa Leonhardt, Gunnar Dahlén, Johan Bylund
Journal of Oral Microbiology - 2021 -
Glycan analysis of human neutrophil granules implicates a maturation-dependent glycosylation
machinery
Vignesh Venkatakrishnan, Regis Dieckmann, I. Loke, H. C. Tjondro, S. Chatterjee, Johan Bylund, M. Thaysen-Andersen, Niclas G. Karlsson, Anna Karlsson-Bengtsson
Journal of Biological Chemistry - 2020 -
Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without
COPD.
Marit Stockfelt, Karin Christenson, Anders Andersson, Lena Björkman, Médea Padra, Bettina Brundin, Koustav Ganguly, Helga Asgeirsdottir, Sara K. Lindén, Ingemar Qvarfordt, Johan Bylund, Anders Lindén
Journal of Innate Immunity - 2020 -
Reply to Julia Volkmann and Sibylle von
Vietinghoff.
Agnes Dahlstrand Rudin, Johan Bylund
Journal of leukocyte biology - 2020 -
In Vivo Transmigrated Human Neutrophils Are Highly Primed for Intracellular Radical Production Induced by Monosodium Urate
Crystals.
Lisa Davidsson, Agnes Dahlstrand Rudin, Felix Peter Sanchez Klose, Alicia Buck, Lena Björkman, Karin Christenson, Johan Bylund
International journal of molecular sciences - 2020 -
Measurement of Respiratory Burst Products, Released or Retained, During Activation of Professional
Phagocytes.
Claes Dahlgren, Halla Björnsdottir, Martina Sundqvist, Karin Christenson, Johan Bylund
Methods in molecular biology (Clifton, N.J.) Vol 2087. - 2020 -
Intracellular neutrophil oxidants: From laboratory curiosity to clinical
reality
Claes Dahlgren, Anna Karlsson, Johan Bylund
Journal of Immunology - 2019 -
Reduced sialyl-Lewis(x) on salivary MUC7 from patients with burning mouth
syndrome
Shikha Acharya, Chunsheng Jin, Johan Bylund, Q. J. Shen, M. Kamali-Moghaddam, Mats Jontell, Anette Carlén, Niclas G. Karlsson
Molecular Omics - 2019 -
Neutrophil recruitment to inflamed joints can occur without cellular
priming.
Lena Björkman, Karin Christenson, Lisa Davidsson, Jonas Mårtensson, Firoozeh Amirbeagi, Amanda Welin, Huamei Forsman, Anna Karlsson, Claes Dahlgren, Johan Bylund
Journal of leukocyte biology - 2019 -
DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human
Neutrophils.
Alicia Buck, Felix P Klose, Vignesh Venkatakrishnan, Claes Dahlgren, Karin Christenson, Johan Bylund
ImmunoHorizons - 2019 -
Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE
mutations
Q. Liu, Martina Sundqvist, W. Y. Li, André Holdfeldt, L. Zhang, Lena Björkman, Johan Bylund, Claes Dahlgren, C. Wang, X. D. Zhao, Huamei Forsman
Bmc Pediatrics - 2019 -
Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in
asthma
M. Erriah, K. Pabreja, M. Fricker, K. J. Baines, L. E. Donnelly, Johan Bylund, Anna Karlsson, J. L. Simpson, Journal Of Biological Chemistry V. P. Rlsson Sr
Respiratory Research - 2019 -
Determination of Subset-Restricted Anti-neutrophil Cytoplasmic Antibodies (ANCA) by Immunofluorescence
Cytochemistry.
Firoozeh Amirbeagi, Amanda Welin, Pontus Thulin, Johan Bylund
Methods in molecular biology (Clifton, N.J.) - 2019 -
Importance of Virulence Factors for the Persistence of Oral Bacteria in the Inflamed Gingival Crevice and in the Pathogenesis of Periodontal
Disease
Gunnar Dahlén, Amina Basic, Johan Bylund
Journal of Clinical Medicine - 2019 -
The Role of Formyl Peptide Receptors for Immunomodulatory Activities of Antimicrobial Peptides and
Peptidomimetics
S. L. Skovbakke, André Holdfeldt, Huamei Forsman, Johan Bylund, H. Franzyk
Current Pharmaceutical Design - 2018 -
Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell
function
Martina Sundqvist, Amanda Welin, Jonas Elmwall, Veronica Osla, U. J. Nilsson, H. Leffler, Johan Bylund, Anna Karlsson
Journal of Leukocyte Biology - 2018 -
Galectin-3 is a target for proteases involved in the virulence of Staphylococcus
aureus.
Jonas Elmwall, Jakub Kwiecinski, Manli Na, Abukar Ali, Veronica Osla, Lindsey Shaw, Wanzhong Wang, Karin Sävman, Elisabet Josefsson, Johan Bylund, Tao Jin, Amanda Welin, Anna Karlsson
Infection and immunity - 2017 -
Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient
Phagocytes
Martina Sundqvist, Karin Christenson, Halla Björnsdottir, Veronica Osla, Anna Karlsson, Claes Dahlgren, D. P. Speert, Anders Fasth, K. L. Brown, Johan Bylund
Frontiers in Immunology - 2017 -
Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent
Pathway.
Halla Björnsdottir, Agnes Dahlstrand Rudin, Felix P Klose, Jonas Elmwall, Amanda Welin, Marios Stylianou, Karin Christenson, Constantin F Urban, Huamei Forsman, Claes Dahlgren, Anna Karlsson, Johan Bylund
Frontiers in immunology - 2017 -
Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in
question
Malene Winther, André Holdfeldt, Martina Sundqvist, Zahra Rajabkhani, Michael Gabl, Johan Bylund, Claes Dahlgren, Huamei Forsman
Plos One - 2017 -
The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue
Recruitment
Lena Björkman, Jonas Martensson, Malene Winther, Michael Gabl, André Holdfeldt, Martin Uhrbom, Johan Bylund, A. H. Hansen, S. K. Pandey, T. Ulven, Huamei Forsman, Claes Dahlgren
Molecular and Cellular Biology - 2016 -
A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk
mechanism.
Michael Gabl, André Holdfeldt, Malene Winther, Tudor I Oprea, Johan Bylund, Claes Dahlgren, Huamei Forsman
Biochimica et biophysica acta - 2016 -
Staphylokinase controls Staphylococcus aureus biofilm formation and detachment through host plasminogen
activation.
Jakub Kwiecinski, Marijke Peetermans, Laurens Liesenborghs, Manli Na, Halla Björnsdottir, Xuefeng Zhu, Gunnar Jacobsson, Bengt R Johansson, Joan A Geoghegan, Timothy J Foster, Elisabet Josefsson, Johan Bylund, Peter Verhamme, Tao Jin
The Journal of infectious diseases - 2016 -
Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen
species.
Per Wekell, Halla Björnsdottir, Lena Björkman, Martina Sundqvist, Karin Christenson, Veronica Osla, Stefan Berg, Anders Fasth, Amanda Welin, Johan Bylund, Anna Karlsson
Rheumatology (Oxford, England) - 2016 -
Quantification of heterotypic granule fusion in human neutrophils by imaging flow
cytometry.
Halla Björnsdottir, Amanda Welin, Claes Dahlgren, Anna Karlsson, Johan Bylund
Data in brief - 2016 -
TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell
Responses
Rebecca E Riise, Elin Bernson, Johan Aurelius, Anna Martner, S. Pesce, M. Della Chiesa, E. Marcenaro, Johan Bylund, Kristoffer Hellstrand, L. Moretta, A. Moretta, Fredrik Bergh Thorén
Journal of Immunology - 2015 -
P2Y2 receptor signaling in neutrophils Is regulated from inside by a novel cytoskeleton-dependent
mechanism.
Michael Gabl, Malene Winther, Amanda Welin, Anna Karlsson, Tudor I Oprea, Johan Bylund, Claes Dahlgren, Huamei Forsman
Experimental cell research - 2015 -
Phagocyte interactions with Mycobacterium tuberculosis - Simultaneous analysis of phagocytosis, phagosome maturation and intracellular replication by imaging flow
cytometry.
Jessika Johansson, Anna Karlsson, Johan Bylund, Amanda Welin
Journal of immunological methods - 2015 -
Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen
species.
Halla Björnsdottir, Amanda Welin, Erik Michaëlsson, Veronica Osla, Stefan Berg, Karin Christenson, Martina Sundqvist, Claes Dahlgren, Anna Karlsson, Johan Bylund
Free radical biology & medicine - 2015 -
CTLA4-Ig but not anti-TNF therapy promotes staphylococcal septic arthritis in
mice.
Abukar Ali, Amanda Welin, Jan-Christoph Schwarze, Mattias Svensson, Manli Na, Anders Jarneborn, Malin Magnusson, Majd Mohammad, Jakub Kwiecinski, Elisabet Josefsson, Johan Bylund, Rille Pullerits, Tao Jin
The Journal of infectious diseases - 2015 -
CFP-10 from Mycobacterium tuberculosis Selectively Activates Human Neutrophils through a Pertussis Toxin-Sensitive Chemotactic
Receptor.
Amanda Welin, Halla Björnsdottir, Malene Winther, Karin Christenson, Tudor I Oprea, Anna Karlsson, Huamei Forsman, Claes Dahlgren, Johan Bylund
Infection and immunity - 2015 -
Olfactomedin-4 autoantibodies give unusual c-ANCA staining patterns with reactivity to a subpopulation of
neutrophils.
Firoozeh Amirbeagi, Pontus Thulin, Rille Pullerits, Bo Pedersen, Bengt A. Andersson, Claes Dahlgren, Amanda Welin, Johan Bylund
Journal of leukocyte biology - 2015 -
Collection of in vivo transmigrated neutrophils from human
skin.
Karin Christenson, Lena Björkman, Lisa Davidsson, Anna Karlsson, Per Follin, Claes Dahlgren, Johan Bylund
Methods in molecular biology (Clifton, N.J.) - 2014 -
Turning Chemoattractant Receptors On and Off with Conventional Ligands and Allosteric Modulators: Recent advances in formyl peptide receptor signaling and
regulation
Johan Bylund, Michael Gabl, Malene Winther, Karin Önnheim, Claes Dahlgren, Huamei Forsman
Inflammation and cell signaling - 2014 -
Antibacterial activity of pepducins, allosterical modulators of formyl Peptide receptor
signaling.
Malene Winther, Michael Gabl, Tudor I Oprea, Bodil Jönsson, Francois Boulay, Johan Bylund, Claes Dahlgren, Huamei Forsman
Antimicrobial agents and chemotherapy - 2014 -
A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of
FPR2
Michael Gabl, Malene Winther, Sarah Line Skovbakke, Johan Bylund, Claes Dahlgren, Huamei Forsman
Plos One - 2014 -
Signal Regulatory Protein Alpha Is Present in Several Neutrophil Granule Populations and Is Rapidly Mobilized to the Cell Surface to Negatively Fine-Tune Neutrophil Accumulation in
Inflammation.
Asa Stenberg, Anna Karlsson, Elisabeth Feuk-Lagerstedt, Karin Christenson, Johan Bylund, Anna Oldenborg, Liselotte Vesterlund, Takashi Matozaki, Janove Sehlin, Per-Arne Oldenborg
Journal of Innate Immunity - 2014 -
A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce
superoxide.
Karin Önnheim, Karin Christenson, Michael Gabl, Joachim C Burbiel, Christa E Müller, Tudor I Oprea, Johan Bylund, Claes Dahlgren, Huamei Forsman
Experimental cell research - 2014 -
Measurement of respiratory burst products, released or retained, during activation of professional
phagocytes.
Johan Bylund, Halla Björnsdottir, Martina Sundqvist, Anna Karlsson, Claes Dahlgren
Methods in molecular biology (Clifton, N.J.) - 2014 -
Midkine is expressed and differentially processed during COPD exacerbations and ventilator-associated pneumonia associated with Staphylococcus aureus
infection.
Helena M Linge, Cecilia Andersson, Sara L Nordin, Anders I Olin, Ann-Cathrine Petersson, Matthias Mörgelin, Amanda Welin, Johan Bylund, Leif Bjermer, Jonas Erjefält, Arne Egesten
Molecular medicine (Cambridge, Mass.) - 2013 -
Increased intracellular oxygen radical production in neutrophils during febrile episodes of PFAPA
syndrome.
Martina Sundqvist, Per Wekell, Veronica Osla, Johan Bylund, Karin Christenson, Karin Sävman, Dirk Foell, David A Cabral, Anders Fasth, Stefan Berg, Kelly Brown, Anna Karlsson
Arthritis and rheumatism - 2013 -
Inhibition of phospholipase A(2) abrogates intracellular processing of NADPH-oxidase derived reactive oxygen species in human
neutrophils.
Halla Björnsdottir, Daniel Granfeldt, Amanda Welin, Johan Bylund, Anna Karlsson
Experimental cell research - 2013 -
Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different
Receptors.
Karin Christenson, Lena Björkman, Sofie Ahlin, Maja Olsson, Kajsa Sjöholm, Anna Karlsson, Johan Bylund
Frontiers in immunology - 2013 -
The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor
loop.
Huamei Forsman, Johan Bylund, Tudor I Oprea, Anna Karlsson, Francois Boulay, Marie-Josephe Rabiet, Claes Dahlgren
Biochimica et biophysica acta - 2013 -
A simple skin blister technique for the study of in vivo transmigration of human
leukocytes.
Lisa Davidsson, Lena Björkman, Karin Christenson, Mikael Alsterholm, Charlotta Movitz, Fredrik Bergh Thorén, Anna Karlsson, Amanda Welin, Johan Bylund
Journal of immunological methods - 2013 -
The Human Neutrophil Subsets Defined by the Presence or Absence of OLFM4 Both Transmigrate into Tissue In Vivo and Give Rise to Distinct NETs In
Vitro.
Amanda Welin, Firoozeh Amirbeagi, Karin Christenson, Lena Björkman, Halla Björnsdottir, Huamei Forsman, Claes Dahlgren, Anna Karlsson, Johan Bylund
PloS one - 2013 -
Regulation of Neutrophil Apoptosis Differs after in vivo Transmigration to Skin Chambers and Synovial Fluid: A Role for Inflammasome-Dependent Interleukin-1 beta
Release
Karin Christenson, Lena Björkman, Anna Karlsson, Johan Bylund
Journal of Innate Immunity - 2013 -
Cord-forming mycobacteria induce DNA meshwork formation by human peripheral blood mononuclear
cells
Bodil Jönsson, Johan Bylund, Bengt R Johansson, Esbjörn Telemo, Agnes E Wold
Pathogens and Disease - 2013 -
Reactivation of Desensitized Formyl Peptide Receptors by Platelet Activating Factor: A Novel Receptor Cross Talk Mechanism Regulating Neutrophil Superoxide Anion
Production
Huamei Forsman, Karin Önnheim, Emil Andréasson, Karin Christenson, Anna Karlsson, Johan Bylund, Claes Dahlgren
Plos One - 2013 -
Lectins Offer New Perspectives in the Development of Macrophage-Targeted Therapies for
COPD/Emphysema
V. R. Mukaro, Johan Bylund, G. Hodge, M. Holmes, H. Jersmann, P. N. Reynolds, S. Hodge
Plos One - 2013 -
Human NK Cells induce neutrophil apoptosis via an NKp46- and Fas-dependent
mechanism.
Fredrik Bergh Thorén, Rebecca E Riise, Jenny Ousbäck, Mariella Della Chiesa, Mikael Alsterholm, Emanuela Marcenaro, Silvia Pesce, Carola Prato, Claudia Cantoni, Johan Bylund, Lorenzo Moretta, Alessandro Moretta
Journal of immunology (Baltimore, Md. : 1950) - 2012 -
Analyzing cell death events in cultured
leukocytes.
Karin Christenson, Fredrik Bergh Thorén, Johan Bylund
Methods in molecular biology (Clifton, N.J.) - 2012 -
Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen
Species
Huamei Forsman, Karin Christenson, Johan Bylund, Claes Dahlgren
Infection and Immunity - 2012 -
Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered
activities.
Ola Kilsgård, Pia Andersson, Martin Malmsten, Sara L Nordin, Helena M Linge, Mette Eliasson, Eva Sörenson, Jonas S Erjefält, Johan Bylund, Anders I Olin, Ole E Sørensen, Arne Egesten
American journal of respiratory cell and molecular biology - 2012 -
Escape of Mycobacterium tuberculosis from oxidative killing by
neutrophils.
Björn Corleis, Daniel Korbel, Robert Wilson, Johan Bylund, Ronnie Chee, Ulrich E Schaible
Cellular microbiology - 2012 -
Human Synovial Lubricin Expresses Sialyl Lewis x Determinant and Has L-selectin Ligand
Activity
Chunsheng Jin, Anna-Karin H Ekwall, Johan Bylund, Lena Björkman, R. P. Estrella, J. M. Whitelock, T. Eisler, Maria Bokarewa, Niclas G. Karlsson
Journal of Biological Chemistry - 2012 -
In vivo-transmigrated human neutrophils are resistant to antiapoptotic
stimulation.
Karin Christenson, Lena Björkman, Jennie Karlsson, Martina Sundqvist, Charlotta Movitz, David P Speert, Claes Dahlgren, Johan Bylund
Journal of leukocyte biology - 2011 -
Host defense peptide LL-37 selectively reduces proinflammatory macrophage
responses.
Kelly Brown, Grace F T Poon, Darlene Birkenhead, Olga M Pena, Reza Falsafi, Claes Dahlgren, Anna Karlsson, Johan Bylund, Robert E W Hancock, Pauline Johnson
Journal of immunology (Baltimore, Md. : 1950) - 2011 -
A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger
neutrophils.
Jennie Karlsson, Johan Bylund, Charlotta Movitz, Lena Björkman, Huamei Forsman, Claes Dahlgren
Journal of immunological methods - 2010 -
Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what
for?
Johan Bylund, Kelly Brown, Charlotta Movitz, Claes Dahlgren, Anna Karlsson
Free radical biology & medicine - 2010 -
The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the
circulation.
Lena Björkman, John G Raynes, Chandrabala Shah, Anna Karlsson, Claes Dahlgren, Johan Bylund
Arthritis and rheumatism - 2010 -
Mice chronically fed high-fat diet have increased mortality and disturbed immune response in
sepsis.
Louise Strandberg, Margareta Verdrengh, Maria Enge, Niklas Andersson, Sylvie Amu, Karin Önnheim, Anna Benrick, Mikael Brisslert, Johan Bylund, Maria Bokarewa, Staffan Nilsson, John-Olov Jansson
PloS one - 2009 -
The host defense peptide LL-37 selectively permeabilizes apoptotic
leukocytes.
Åse Björstad, Galia Askarieh, Kelly Brown, Karin Christenson, Huamei Forsman, Karin Önnheim, Hsin-Ni Li, Susann Teneberg, Olaf Maier, Dick Hoekstra, Claes Dahlgren, Donald J Davidson, Johan Bylund
Antimicrobial agents and chemotherapy - 2009 -
The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium
channels.
Jennie Karlsson, Anna-Lena Stenfeldt, Marie-Josèphe Rabiet, Johan Bylund, Huamei Forsman, Claes Dahlgren
Cell calcium - 2009 -
Divergent Effects on Phagocytosis by Macrophage-Derived Oxygen
Radicals
Kelly Brown, Karin Christenson, Anna Karlsson, Claes Dahlgren, Johan Bylund
J Innate Immun - 2009 -
Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic
neutrophils.
Anna Karlsson, Karin Christenson, Mustafa Matlak, Åse Björstad, Kelly Brown, Esbjörn Telemo, Emma Salomonsson, Hakon Leffler, Johan Bylund
Glycobiology - 2009 -
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing
macrophages
H. N. Li, P. G. Barlow, Johan Bylund, A. Mackellar, Åse Björstad, J. Conlon, P. S. Hiemstra, C. Haslett, M. Gray, A. J. Simpson, A. G. Rossi, D. J. Davidson
J Leukoc Biol - 2009 -
The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the
agonist
Huamei Forsman, E. Salomonsson, Karin Önnheim, Jennie Karlsson, Åse Björstad, H. Leffler, Johan Bylund, Anna Karlsson, Claes Dahlgren
Glycobiology - 2008 -
Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7-sensitive pathway independent of formyl peptide receptor-like
1
Karin Christenson, Lena Björkman, Carolina Tängemo, Johan Bylund
Journal of Leukocyte Biology - 2008 -
Tumour necrosis factor (TNF)-alpha primes murine neutrophils when triggered via formyl peptide receptor-related sequence 2, the murine orthologue of human formyl peptide receptor-like 1, through a process involving the type I TNF receptor and subcellular granule
mobilization
Karin Önnheim, Johan Bylund, F. Boulay, Claes Dahlgren, Huamei Forsman
Immunology - 2008 -
Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific
events
Huamei Fu, Jennie Karlsson, Lena Björkman, Anna-Lena Stenfeldt, Anna Karlsson, Johan Bylund, Claes Dahlgren
Journal of Immunological Methods - 2008 -
Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor
like-1
Lena Björkman, Jennie Karlsson, Anna Karlsson, M. J. Rabiet, F. Boulay, Huamei Fu, Johan Bylund, Claes Dahlgren
Journal of Leukocyte Biology - 2008 -
Antimicrobial host defence peptides of human neutrophils – roles in innate
immunity
Åse Björstad, Kelly Brown, Huamei Fu, Claes Dahlgren, Anna Karlsson, Johan Bylund
Anti-Infective Agents in Medicinal Chemistry - 2008 -
Phagocyte-derived reactive oxygen species as suppressors of inflammatory
disease
Lena Björkman, Claes Dahlgren, Anna Karlsson, Kelly Brown, Johan Bylund
Arthritis & Rheumatism - 2008 -
ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous
disease
Kelly Brown, Johan Bylund, K. L. Macdonald, G. X. Song-Zhao, M. R. Elliott, R. Falsafi, R. E. Hancock, D. P. Speert
Clin Immunol - 2008 -
Measurement of respiratory burst products generated by professional
phagocytes
Claes Dahlgren, Anna Karlsson, Johan Bylund
Neutrophil Methods and Protocols. Mark T. QuinnFrank R. DeLeoGary M. Bokoch (red.) - 2007 -
The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptide receptor but not the formyl peptide receptor like
1
Anna-Lena Stenfeldt, Jennie Karlsson, Christine Wennerås, Johan Bylund, Huamei Fu, Claes Dahlgren
Biochem Pharmacol - 2007 -
Cyclosporin H, Boc-MLF and Boc-FLFLF are Antagonists that Preferentially Inhibit Activity Triggered Through the Formyl Peptide
Receptor
Anna-Lena Stenfeldt, Jennie Karlsson, Christine Wennerås, Johan Bylund, Huamei Fu, Claes Dahlgren
Inflammation - 2007 -
Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kappa
B
Johan Bylund, K. L. Macdonald, Kelly Brown, P. Mydel, Vincent Collins, R. E. Hancock, D. P. Speert
Eur J Immunol - 2007 -
Ligand recognition and activation of formyl peptide receptors in
neutrophils
Huamei Fu, Jenny Karlsson, Johan Bylund, Charlotta Movitz, Anna Karlsson, Claes Dahlgren
J Leukoc Biol - 2006 -
The peptide Trp-Lys-Tyr-Met-Val-D-Met activates neutrophils through the formyl peptide receptor only when signaling through the formylpeptide receptor like 1 is blocked. A receptor switch with implications for signal transduction studies with inhibitors and receptor
antagonists
Jennie Karlsson, Huamei Fu, F. Boulay, Johan Bylund, Claes Dahlgren
Biochemical pharmacology - 2006 -
IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid
cells
D. J. Davidson, A. J. Currie, D. M. Bowdish, K. L. Brown, C. M. Rosenberger, R. C. Ma, Johan Bylund, P. A. Campsall, A. Puel, C. Picard, J. L. Casanova, S. E. Turvey, R. E. Hancock, R. S. Devon, D. P. Speert
J Immunol - 2006 -
Exopolysaccharides from Burkholderia cenocepacia inhibit neutrophil chemotaxis and scavenge reactive oxygen
species
Johan Bylund, L. A. Burgess, P. Cescutti, R. K. Ernst, D. P. Speert
J Biol Chem - 2006 -
Interleukin-8-derived peptide has antibacterial
activity
Åse Björstad, Huamei Fu, Anna Karlsson, Claes Dahlgren, Johan Bylund
Antimicrobial agents and chemotherapy - 2005 -
Chronic granulomatous disease: from genetic defect to clinical
presentation
Johan Bylund, D. Goldblatt, D. P. Speert
Adv Exp Med Biol - 2005 -
Burkholderia cenocepacia induces neutrophil necrosis in chronic granulomatous
disease
Johan Bylund, P. A. Campsall, R. C. Ma, B. A. Conway, D. P. Speert
J Immunol - 2005 -
Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed
neutrophils
Johan Bylund, Sara Pellmé, Huamei Fu, Ulf-Henrik Mellqvist, Kristoffer Hellstrand, Anna Karlsson, Claes Dahlgren
BMC cell biology - 2004 -
The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for
interleukin-8
Huamei Fu, Johan Bylund, Anna Karlsson, Sara Pellmé, Claes Dahlgren
Immunology - 2004 -
A bactericidal cecropin-A peptide with a stabilized alpha-helical structure possess an increased killing capacity but no proinflammatory
activity
Huamei Fu, Åse Björstad, Claes Dahlgren, Johan Bylund
Inflammation - 2004 -
Production of exopolysaccharide by Burkholderia cenocepacia results in altered cell-surface interactions and altered bacterial clearance in
mice
B. A. Conway, K. K. Chu, Johan Bylund, E. Altman, D. P. Speert
J Infect Dis - 2004 -
Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial
chemotherapy
Huamei Fu, Claes Dahlgren, Johan Bylund
Antimicrob Agents Chemother - 2003 -
Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular
calcium
Johan Bylund, Åse Björstad, Daniel Granfeldt, Anna Karlsson, Charlotte Woschnagg, Claes Dahlgren
J Biol Chem - 2003 -
Outer membrane protein A deficient Escherichia coli activates neutrophils to produce superoxide and shows increased susceptibility to antibacterial
peptides
Huamei Fu, A. A. Belaaouaj, Claes Dahlgren, Johan Bylund
Microbes Infect - 2003 -
NADPH-oxidase activation in murine neutrophils via formyl peptide
receptors
Johan Bylund, Marie Samuelsson, Vincent Collins, Anna Karlsson
Exp Cell Res - 2003 -
Recognition by leukocyte formyl peptide receptors. Promiscuous binding or pattern
recognition?
Johan Bylund
2002 -
Immunostimulatory DNA induces degranulation and NADPH-oxidase activation in human neutrophils while concomitantly inhibiting chemotaxis and
phagocytosis
Johan Bylund, Marie Samuelsson, Andrej Tarkowski, Anna Karlsson, Vincent Collins
Eur J Immunol - 2002 -
Lipopolysaccharide-induced granule mobilization and priming of the neutrophil response to Helicobacter pylori peptide Hp(2-20), which activates formyl peptide receptor-like
1
Johan Bylund, Anna Karlsson, F. Boulay, Claes Dahlgren
Infect Immun - 2002 -
Problems in identifying microbial-derived neutrophil activators, focusing on Helicobacter
pylori
Johan Bylund, Claes Dahlgren
Trends Microbiol - 2002 -
Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter
pylori
Johan Bylund, T. Christophe, F. Boulay, Thomas Nyström, Anna Karlsson, Claes Dahlgren
Antimicrob Agents Chemother - 2001 -
A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and
apoptosis
Åsa Betten, Johan Bylund, T. Christophe, F. Boulay, Ana Romero, Kristoffer Hellstrand, Claes Dahlgren
J Clin Invest - 2001