Key Publications

2022

Neural Pathway for Gut Feelings: Vagal Interoceptive Feedback From the Gastrointestinal Tract Is a Critical Modulator of Anxiety-like Behavior.
Krieger JP, Asker M, van der Velden P, Börchers S, Richard JE, Maric I, Longo F, Singh A, de Lartigue G, Skibicka KP.
Biol Psychiatry. 2022 May 18:S0006-3223(22)01253-7.

Glycoinformatics in the Artificial Intelligence Era.
Bojar D, Lisacek F.
Chem Rev. 2022 Aug 12.

Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures.
Soták M, Rajan MR, Clark M, Harms M, Rani A, Kraft JD, Tandio D, Shen T, Borkowski K, Fiehn O, Newman JW, Quiding-Järbrink M, Biörserud C, Apelgren P, Staalesen T, Hagberg CE, Boucher J, Wallenius V, Lange S, Börgeson E.
iScience. 2022 Jun 11;25(7):104602.

From an Empty Stomach to Anxiolysis: Molecular and Behavioral Assessment of Sex Differences in the Ghrelin Axis of Rats.
Börchers S, Krieger JP, Maric I, Carl J, Abraham M, Longo F, Asker M, Richard JE, Skibicka KP.
Front Endocrinol (Lausanne). 2022 Jun 16;13:901669.

Using a Clinicopathologic and Gene Expression (CP-GEP) Model to Identify Stage I-II Melanoma Patients at Risk of Disease Relapse.
Mulder EEAP, Johansson I, Grünhagen DJ, Tempel D, Rentroia-Pacheco B, Dwarkasing JT, Verver D, Mooyaart AL, van der Veldt AAM, Wakkee M, Nijsten TEC, Verhoef C, Mattsson J, Ny L, Hollestein LM, Olofsson Bagge R.
Cancers (Basel). 2022 Jun 9;14(12):2854.

Imaging tau pathology in Alzheimer's disease with positron emission tomography: lessons learned from imaging-neuropathology validation studies.
Moscoso A, Wren MC, Lashley T, Arstad E, Murray ME, Fox NC, Sander K, Schöll M.
Mol Neurodegener. 2022 Jun 3;17(1):39.

The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases - A multicenter cohort study.
Holmberg CJ, Ny L, Hieken TJ, Block MS, Carr MJ, Sondak VK, Örtenwall C, Katsarelias D, Dimitriou F, Menzies AM, Saw RP, Rogiers A, Straker RJ 3rd, Karakousis G, Applewaite R, Pallan L, Han D, Vetto JT, Gyorki DE, Tie EN, Vitale MG, Ascierto PA, Dummer R, Cohen J, Hui JY, Schachter J, Asher N, Helgadottir H, Chai H, Kroon H, Coventry B, Rothermel LD, Sun J, Carlino MS, Duncan Z, Broman K, Weber J, Lee AY, Berman RS, Teras J, Ollila DW, Long GV, Zager JS, van Akkooi A, Olofsson Bagge R.
Eur J Cancer. 2022 Jul;169:210-222.

KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer.
Eklund EA, Wiel C, Fagman H, Akyürek LM, Raghavan S, Nyman J, Hallqvist A, Sayin VI.
Cancers (Basel). 2022 Apr 20;14(9):2063.

The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis.
Erttmann SF, Swacha P, Aung KM, Brindefalk B, Jiang H, Härtlova A, Uhlin BE, Wai SN, Gekara NO.
Immunity. 2022 May 10;55(5):847-861.

Brain charts for the human lifespan.
Bethlehem RAI, Seidlitz J, White SR, Vogel JW, Anderson KM, …Schöll M… et al.
Nature. 2022 Apr 6.

Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis.
Kraft JD, Blomgran R, Bergström I, Soták M, Clark M, Rani A, Rajan MR, Dalli J, Nyström S, Quiding-Järbrink M, Bromberg J, Skoog P, Börgeson E.
FASEB J. 2022 Mar;36(3):e22173.

FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
Dolatabadi S, Jonasson E, Andersson L, Luna Santamaría M, Lindén M, Österlund T, Åman P, Ståhlberg A.
Front Oncol. 2022 Feb 3;12:816894.

Big data analysis of ASM retention rates and expert ASM algorithm: A comparative study.
Håkansson S, Zelano J.
Epilepsia. 2022 Mar 24.

Sex and Species Differences in the Development of Diet-Induced Obesity and Metabolic Disturbances in Rodents.
Maric I, Krieger JP, van der Velden P, Börchers S, Asker M, Vujicic M, Wernstedt Asterholm I, Skibicka KP.
Front Nutr. 2022 Feb 17;9:828522.

Structural insights into host-microbe glycointeractions.
Lundström J, Bojar D.
Curr Opin Struct Biol. 2022 Apr;73:102337

CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial design.
Moscoso A, Karikari TK, Grothe MJ, Ashton NJ, Lantero-Rodriguez J, Snellman A, Zetterberg H, Blennow K, Schöll M.
Alzheimers Dement. 2022 Feb 28.

A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities.
Bojar D, Meche L, Meng G, Eng W, Smith DF, Cummings RD, Mahal LK.
ACS Chem Biol. 2022 Jan 27.

2021

LectinOracle: A Generalizable Deep Learning Model for Lectin-Glycan Binding Predictio.
Lundstrøm J, Korhonen E, Lisacek F, Bojar D.
Adv Sci (Weinh). 2021 Dec 4:e2103807.

Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease.
Govaere O, Petersen SK, Martinez-Lopez N, Wouters J, Van Haele M, Mancina RM, Jamialahmadi O, Bilkei-Gorzo O, Lassen PB, Darlay R, Peltier J, Palmer JM, Younes R, Tiniakos D, Aithal GP, Allison M, Vacca M, Göransson M, Berlinguer-Palmini R, Clark JE, Drinnan MJ, Yki-Järvinen H, Dufour JF, Ekstedt M, Francque S, Petta S, Bugianesi E, Schattenberg JM, Day CP, Cordell HJ, Topal B, Clément K, Romeo S, Ratziu V, Roskams T, Daly AK, Anstee QM, Trost M, Härtlova A.
J Hepatol. 2021 Dec 20:S0168-8278(21)02254-6.

Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy.
Larsson D, Baftiu A, Johannessen Landmark C, von Euler M, Kumlien E, Åsberg S, Zelano J.
JAMA Neurol. 2021 Dec 13:e214584.

Structural basis of DegP protease temperature-dependent activation.
Šulskis D, Thoma J, Burmann BM.
Sci Adv. 2021 Dec 10;7(50):eabj1816.

Changes in lung function in European adults born between 1884 and 1996 and implications for the diagnosis of lung disease: a cross-sectional analysis of ten population-based studies.
Allinson JP, Afzal S, Çolak Y, Jarvis D, Backman H, van den Berge M, Boezen HM, Breyer MK, Breyer-Kohansal R, Brusselle G, Burghuber OC, Faner R, Hartl S, Lahousse L, Langhammer A, Lundbäck B, Nwaru BI, Rönmark E, Vikjord SAA, Vonk JM, Wijnant SRA, Lange P, Nordestgaard BG, Olvera N, Agusti A, Donaldson GC, Wedzicha JA, Vestbo J, Vanfleteren LEGW; CADSET Clinical Research Collaboration.
Lancet Respir Med. 2021 Oct 4:S2213-2600(21)00313-1.

Digital Quantification of Chemical Oligonucleotide Synthesis Errors.
Filges S, Mouhanna P, Ståhlberg A.
Clin Chem. 2021 Oct 1;67(10):1384-1394.

Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce.
Li Q, Hagberg CE, Silva Cascales H, Lang S, Hyvönen MT, Salehzadeh F, Chen P, Alexandersson I, Terezaki E, Harms MJ, Kutschke M, Arifen N, Krämer N, Aouadi M, Knibbe C, Boucher J, Thorell A, Spalding KL.
Nat Med. 2021 Oct 4.

Meta-Analysis of Isolated Hepatic Perfusion and Percutaneous Hepatic Perfusion as a Treatment for Uveal Melanoma Liver Metastases.
Bethlehem MS, Katsarelias D, Olofsson Bagge R.
Cancers (Basel). 2021 Sep 21;13(18):4726.

Monitoring circulating tumor-DNA during surgical treatment in patients with gastrointestinal stromal tumors.
Johansson G, Berndsen M, Lindskog S, Österlund T, Fagman H, Muth A, Ståhlberg A.
Mol Cancer Ther. 2021 Sep 22:molcanther.0403.2021.

Deep learning from MRI-derived labels enables automatic brain tissue classification on human brain CT.
Srikrishna M, Pereira JB, Heckemann RA, Volpe G, van Westen D, Zettergren A, Kern S, Wahlund LO, Westman E, Skoog I, Schöll M.
Neuroimage. 2021 Sep 25;244:118606.

Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders.
Kurzawa-Akanbi M, Tammireddy S, Fabrik I, Gliaudelytė L, Doherty MK, Heap R, Matečko-Burmann I, Burmann BM, Trost M, Lucocq JM, Gherman AV, Fairfoul G, Singh P, Burté F, Green A, McKeith IG, Härtlova A, Whitfield PD, Morris CM.
Acta Neuropathol. 2021 Sep 13.

Microglial activation and tau propagate jointly across Braak stages.
Pascoal TA, Benedet AL, Ashton NJ, Kang MS, Therriault J, Chamoun M, Savard M, Lussier FZ, Tissot C, Karikari TK, Ottoy J, Mathotaarachchi S, Stevenson J, Massarweh G, Schöll M, de Leon MJ, Soucy JP, Edison P, Blennow K, Zetterberg H, Gauthier S, Rosa-Neto P.
Nat Med. 2021 Aug 26.

Menopausal hormone therapy and women's health: An umbrella review.
Zhang GQ, Chen JL, Luo Y, Mathur MB, Anagnostis P, Nurmatov U, Talibov M, Zhang J, Hawrylowicz CM, Lumsden MA, Critchley H, Sheikh A, Lundbäck B, Lässer C, Kankaanranta H, Lee SH, Nwaru BI.
PLoS Med. 2021 Aug 2;18(8):e1003731.

Using graph convolutional neural networks to learn a representation for glycans.
Burkholz R, Quackenbush J, Bojar D.
Cell Rep. 2021 Jun 15;35(11):109251.

Unambiguous Tracking of Protein Phosphorylation by Fast High-Resolution FOSY NMR*.
Lesovoy DM, Georgoulia PS, Diercks T, Matečko-Burmann I, Burmann BM, Bocharov EV, Bermel W, Orekhov VY.
Angew Chem Int Ed Engl. 2021 Jun 18.

Construction of Caffeine-Inducible Gene Switches in Mammalian Cells.
Bojar D.
Methods Mol Biol. 2021;2312:159-168.

Hormone replacement therapy and asthma onset in menopausal women: National cohort study.
Shah SA, Tibble H, Pillinger R, McLean S, Ryan D, Critchley H, Price D, Hawrylowicz CM, Simpson CR, Soyiri IN, Appiagyei F, Sheikh A, Nwaru BI.
J Allergy Clin Immunol. 2021 May;147(5):1662-1670.

Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics.
Morigny P, Boucher J, Arner P, Langin D. 
Nat Rev Endocrinol. 2021 May;17(5):276-295. 

Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology. 
Ashton NJ, Pascoal TA, Karikari TK, Benedet AL, Lantero-Rodriguez J, Brinkmalm G, Snellman A, Schöll M, Troakes C, Hye A, Gauthier S, Vanmechelen E, Zetterberg H, Rosa-Neto P, Blennow K. 
Acta Neuropathol. 2021 May;141(5):709-724. 

Bi-allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis-like disease. 
Sofou K, Meier K, Sanderson LE, Kaminski D, Montoliu-Gaya L, Samuelsson E, Blomqvist M, Agholme L, Gärtner J, Mühlhausen C, Darin N, Barakat TS, Schlotawa L, van Ham T, Asin Cayuela J, Sterky FH. 
EMBO Mol Med. 2021 May 7;13(5):e13376. 

Recovery after breast cancer surgery following a recommendation of physical activity pre- and postoperatively (PhysSURG-B)-a randomized clinical trial. 
Heiman J, Haglind E, Olofsson Bagge R. 
Br J Surg. 2021 May 5:znab136. 

CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway. 
Montoliu-Gaya L, Tietze D, Kaminski D, Mirgorodskaya E, Tietze AA, Sterky FH. 
EMBO Rep. 2021 Apr 7;22(4):e51349. 

Post-traumatic epilepsy in adults: a nationwide register-based study. 
Karlander M, Ljungqvist J, Zelano J. 
J Neurol Neurosurg Psychiatry. 2021 Mar 9;92(6):617-21. 

Argonaute Proteins Take Center Stage in Cancers. 
Nowak I, Sarshad AA. 
Cancers (Basel). 2021 Feb 13;13(4):788. 

Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum.Moscoso A, Grothe MJ, Ashton NJ, Karikari TK, Rodriguez JL, Snellman A, Suárez-Calvet M, Zetterberg H, Blennow K, Schöll M; Alzheimer’s Disease Neuroimaging Initiative.
Brain. 2021 Feb 12;144(1):325-339.

Reduced [18F]flortaucipir retention in white matter hyperintensities compared to normal-appearing white matter.
Moscoso A, Grothe MJ, Schöll M; Alzheimer’s Disease Neuroimaging Initiative. 
Eur J Nucl Med Mol Imaging. 2021 Jan 21. 

Prehospital lactate levels in blood as a seizure biomarker: A multi-center observational study.
Magnusson C, Herlitz J, Höglind R, Wennberg P, Edelvik Tranberg A, Axelsson C, Zelano J. Epilepsia. 2021 Jan 8. 

Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease. 
Moscoso A, Grothe MJ, Ashton NJ, Karikari TK, Lantero Rodríguez J, Snellman A, Suárez-Calvet M, Blennow K, Zetterberg H, Schöll M; Alzheimer’s Disease Neuroimaging Initiative. JAMA Neurol. 2021 Jan 11:e204986.

2020

Preparation of Bacterial Outer Membrane Vesicles for Characterisation of Periplasmic Proteins in Their Native Environment. 
Thoma J, Burmann BM. 
Bio Protoc. 2020 Dec 20;10(24):e3853. 

Epilepsy after brain infection in adults: A register-based population-wide study. 
Zelano J, Westman G. 
Neurology. 2020 Dec 15;95(24):e3213-e3220. 

Hormone replacement therapy and asthma onset in menopausal women: National cohort study. 
Shah SA, Tibble H, Pillinger R, McLean S, Ryan D, Critchley H, Price D, Hawrylowicz CM, Simpson CR, Soyiri IN, Appiagyei F, Sheikh A, Nwaru BI.  
J Allergy Clin Immunol. 2020 Dec 3:S0091-6749(20)31697-3. 

Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum. Moscoso A, Grothe MJ, Ashton NJ, Karikari TK, Rodriguez JL, Snellman A, Suárez-Calvet M, Zetterberg H, Blennow K, Schöll M; Alzheimer’s Disease Neuroimaging Initiative. 
Brain. 2020 Nov 30:awaa399. 

Hormonal contraception and the risk of severe asthma exacerbation: 17-year population-based cohort study. 
Nwaru BI, Tibble H, Shah SA, Pillinger R, McLean S, Ryan DP, Critchley H, Price DB, Hawrylowicz CM, Simpson CR, Soyiri IN, Appiagyei F, Sheikh A. 
Thorax. 2020 Nov 23:thoraxjnl-2020-215540. 

The Effect of Beta-Adrenergic Blocking Agents in Cutaneous Melanoma-A Nation-Wide Swedish Population-Based Retrospective Register Study.
Katsarelias D, Eriksson H, Mikiver R, Krakowski I, Nilsson JA, Ny L, Olofsson Bagge R.
Cancers (Basel). 2020 Nov 2;12(11):E3228.

UvrD helicase-RNA polymerase interactions are governed by UvrD's carboxy-terminal Tudor domain.
Kawale AA, Burmann BM.
Commun Biol. 2020 Oct 23;3(1):607.
 
Ultrasensitive DNA Immune Repertoire Sequencing Using Unique Molecular Identifiers.
Johansson G, Kaltak M, Rîmniceanu C, Singh AK, Lycke J, Malmeström C, Hühn M, Vaarala O, Cardell S, Ståhlberg A.
Clin Chem. 2020 Sep 1;66(9):1228-1237.
 
An Obesogenic Dietary Mouse Model of Nonalcoholic Steatohepatitis.
Zarrouki B, Boucher J.
Methods Mol Biol. 2020;2164:121-127.

Recording in-cell NMR-spectra in living mammalian cells.
Matečko-Burmann, I., Burmann, BM. 
Methods Mol. Biol. July 2020, 2141. 

Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts.
Karikari TK, Pascoal TA, Ashton NJ, Janelidze S, Benedet AL, Rodriguez JL, Chamoun M, Savard M, Kang MS, Therriault J, Schöll M, Massarweh G, Soucy J, Höglund K, Brinkmalm G, Mattsson N, Palmqvist S, Gauthier S, Stomrud E, Zetterberg H, Hansson O, Rosa-Neto P, Blennow K.
Lancet Neurology. May 2020, Vol 19, issue 5, P422-433.

An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders.
Ashton NJ, Hye A, Rajkumar AP, Leuzy A, Snowden S, Suárez-Calvet M, Karikari TK, Schöll M, La Joie R, Rabinovici GD, Höglund K, Ballard C, Hortobágyi T, Svenningsson P, Blennow K, Zetterberg H, Aarsland D.
Nat Rev Neurol. 2020 May;16(5):265-284.

Hormonal contraceptives and onset of asthma in reproductive-age women: Population-based cohort study. 
Nwaru BI, Pillinger R, Tibble H, Shah SA, Ryan D, Critchley H, Price D, Hawrylowicz CM, Simpson CR, Soyiri IN, Appiagyei F, Sheikh A.
J Allergy Clin Immunol. 2020 Apr 9. 

Liquid biopsy analysis in cancer diagnostics.
Andersson D, Kubista M, Ståhlberg A.
Mol Aspects Med. 2020 Apr;72:100839. 

Circulating cell-free tumor DNA analysis in pediatric cancers. 
Andersson D, Fagman H, Dalin MG, Ståhlberg A.
Mol Aspects Med. 2020 Apr;72:100819. 

Patient-derived scaffolds uncover breast cancer promoting properties of the microenvironment.
Landberg G, Fitzpatrick P, Isakson P, Jonasson E, Karlsson J, Larsson E, Svanström A, Rafnsdottir S, Persson E, Gustafsson A, Andersson D, Rosendahl J, Petronis S, Ranji P, Gregersson P, Magnusson Y, Håkansson J, Ståhlberg A.
Biomaterials. 2020 Mar;235:119705. 

Ultrasensitive and selective copper (II) detection: introducing a bioinspired and robust sensor.
Müller LK, Duznovic I, Tietze D, Weber W, Ali M, Stein V, Ensinger W, Tietze A.
Chemistry. 2020 Mar 20. 

Maternal iron supplementation in pregnancy and asthma in the offspring: follow-up of a randomised trial in Finland. 
Shaheen SO, Gissler M, Devereux G, Erkkola M, Kinnunen TI, Mcardle H, Sheikh A, Hemminki E, Nwaru BI.
Eur Respir J. 2020 Mar 5. 

Effect of delay between nuclear medicine scanning and sentinel node biopsy on outcome in patients with cutaneous melanoma. 
Moncrieff MD, O'Leary FM, Beadsmoore CJ, Pawaroo D, Heaton MJ, Isaksson K, Olofsson Bagge R.
Br J Surg. 2020 Feb 19.

Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids.
LeBoeuf SE, Wu WL, Karakousi TR, Karadal B, Jackson SR, Davidson SM, Wong KK, Koralov SB, Sayin VI, Papagiannakopoulos T.
Cell Metab. 2020 Feb 4;31(2):339-350.e4. 

Bariatric surgery and the incidence of rheumatoid arthritis - a Swedish Obese Subjects study. Rheumatology (Oxford).
Maglio C, Zhang Y, Peltonen M, Andersson-Assarsson J, Svensson PA, Herder C, Rudin A, Carlsson L.
2020 Feb 1;59(2):303-309. 

Regulation of α-synuclein by chaperones in mammalian cells.
Burmann BM, Gerez JA, Matečko-Burmann I, Campioni S, Kumari P, Ghosh D, Mazur A, Aspholm EE, Šulskis D, Wawrzyniuk M, Bock T, Schmidt A, Rüdiger SGD, Riek R, Hiller S.
Nature. 2020 Jan;577(7788):127-132. 

Does early cognitive decline require the presence of both tau and amyloid-β?
Schöll M, Maass A.
Brain. 2020 Jan 1;143(1):10-13. 

Overuse of short-acting β(2)-agonists in asthma is associated with increased risk of exacerbation and mortality: A nationwide cohort study of the global SABINA programme.
Nwaru BI, Ekström M, Hasvold P, Wiklund F, Telg G, Janson C.
Eur Respir J. 2020 Jan 16. 

2019

Regional times to equilibria and their impact on semi-quantification of [(18)F]AV-1451 uptake
Heurling K, Smith R, Strandberg OT, Schain M, Ohlsson T, Hansson O, Schöll M..
J Cereb Blood Flow Metab. 2019 Nov;39(11):2223-2232. 

Propagation of Tau Pathology: Integrating Insights From Postmortem and In Vivo Studies.
Vogels T, Leuzy A, Cicognola C, Ashton NJ, Smolek T, Novak M, Blennow K, Zetterberg H, Hromadka T, Zilka N, Schöll M. 
Biol Psychiatry. 2019 Oct 3. pii: S0006-3223(19)31744-5.

Targeting Metabolic Bottlenecks in Lung Cancer.
Sayin VI, LeBoeuf SE, Papagiannakopoulos T. 
Trends Cancer. 2019 Aug;5(8):457-459. 

JAK-STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma.
Dolatabadi S, Jonasson E, Lindén M, Fereydouni B, Bäcksten K, Nilsson M, Martner A, Forootan A, Fagman H, Landberg G, Åman P, Ståhlberg A.
Int J Cancer. 2019 Jul 15;145(2):435-449.

BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis.
Wiel C, Le Gal K, Ibrahim MX, Jahangir CA, Kashif M, Yao H, Ziegler DV, Xu X, Ghosh T, Mondal T, Kanduri C, Lindahl P, Sayin VI*, Bergo MO.
Cell. 2019 Jul 11;178(2):330-345.e22. 
*co-corresponding author

Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages.
Guo M', Härtlova A*', Gierliński M, Prescott A, Castellvi J, Losa JH, Petersen SK, Wenzel UA, Dill BD, Emmerich CH, Ramon Y Cajal S, Russell DG, Trost M.*
EMBO J. 2019 Jun 3;38(11).
'contributed equally, *co-corresponding author.

Furry Animal Allergen Component Sensitization and Clinical Outcomes in Adult Asthma and Rhinitis.
Nwaru BI, Suzuki S, Ekerljung L, Sjölander S, Mincheva R, Rönmark EP, Rådinger M, Rönmark E, Borres MP, Lundbäck B, Lötvall J.
J Allergy Clin Immunol Pract. 2019 Apr;7(4):1230-1238.e4. 

Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.
Harms MJ, Li Q, Lee S, Zhang C, Kull B, Hallen S, Thorell A, Alexandersson I, Hagberg CE, Peng XR, Mardinoglu A, Spalding KL, Boucher J.
Cell Rep. 2019 Apr 2;27(1):213-225.e5.

FET family fusion oncoproteins target and compromise the SWI/SNF chromatin remodeling complex.
Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, Dolatabadi S, Vannas C, Luna Santa Maria M, Fagman H, Ståhlberg A*, Åman P*.
EMBO Reports, 2019
* Joint principal investigator

Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy Metabolism.
Mishra D, Richard JE, Maric I, Porteiro B, Häring M, Kooijman S, Musovic S, Eerola K, López-Ferreras L, Peris E, Grycel K, Shevchouk OT, Micallef P, Olofsson CS, Wernstedt Asterholm I, Grill HJ, Nogueiras R, Skibicka KP.
Cell Rep. 2019 Mar 12;26(11):3011-3026.e5.

2018

Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders.
Ossenkoppele R, Rabinovici GD, Smith R, Cho H, Schöll M, Strandberg O, Palmqvist S, Mattsson N, Janelidze S, Santillo A, Ohlsson T, Jögi J, Tsai R, La Joie R, Kramer J, Boxer AL, Gorno-Tempini ML, Miller BL, Choi JY, Ryu YH, Lyoo CH, Hansson O.
Jama, 2018. 320(11): p. 1151-1162.

Clustering of adult-onset diabetes into novel subgroups provides improved prediction of outcome.
Ahlqvist E, Storm P, Käräjämäki A, Martinell M, Dorkhan M, Carlsson A, Vikman P, Prasad RB, Aly DM, Almgren P, Wessman Y, Shaat N, Spégel P, Mulder H, Lindholm E, Melander O, Hansson O, Malmqvist U, Lernmark Å, Lahti K, Forsén T, Tuomi T, Rosengren AH, Groop L.
Lancet Diabetes and Endocrinology. 2018 May;6(5):361-369.

Lateral hypothalamic GLP-1 receptors are critical for the control of food reinforcement, ingestive behavior and body weight
López-Ferreras L, Richard JE, Noble E, Eerola K, Anderberg RH, Nilsson FH, Olandersson K, Kanoski SE, Hayes MR, Skibicka KP.
Mol Psychiatry. 2018 May;23(5):1157-1168.

2017

Transcriptomic characterization of the human cell cycle in individual unsynchronized cells. 
Karlsson J, Kroneis T, Jonasson E, Larsson E, Ståhlberg A. 
J Mol Biol. 2017 Dec 8;429(24):3909-3924. 

Can learning health systems help organisations deliver personalised care? 
Nwaru BI, Friedman C, Halamka J, Sheikh A. 
BMC Med. 2017 Oct 2;15(1):177.

Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes
Axelsson AS, Tubbs E, Mecham B, Chacko S, Nenonen HA, Tang Y, Fahey JW, Derry JMJ, Wollheim CB, Wierup N, Haymond MW, Friend SH, Mulder H, Rosengren AH
Sci Transl Med. 2017 Jun 14;9(394). 

Sox5 regulates adult beta-cell phenotype and is reduced in type 2 diabetes
Axelsson AS, Mahdi T, Nenonen HA, Hänzelmann S, Bagge A, Wendt A, Reinbothe TM, Millstein J, Yang X, Zhang B, Gusmao EG, Shu L, Tang Y, Wang J, Andersson SE, Eliasson L, Artner I, Wollheim CB, Derry JM, Mecham B, Spégel P, Mulder H, Gesteira Costa Filho I, Zhang E, Rosengren AH
Nat Commun, Jun 6;8:15652 2017

Distinct 18F-AV-1451 tau PET retention patterns in early- and late-onset Alzheimer's disease.
Schöll M, Ossenkoppele R, Strandberg O, Palmqvist S; Swedish BioFINDER study, Jögi J, Ohlsson T, Smith R, Hansson O.
Brain, 2017. 140(9): p. 2286-2294.

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