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Madeleine Rådinger

Avd-/Sektionschef, bitr, inst

Avd för invärtesmedicin och klinisk nutrition
Telefon
031-786 67 13
E-post
madeleine.radinger@lungall.gu.se
Besöksadress
Medicinaregatan 1F
413 90 Göteborg
Postadress
Box 424
405 30 Göteborg

Professor

Institutionen för medicin
Telefon
031-786 67 13
E-post
madeleine.radinger@lungall.gu.se

Om Madeleine Rådinger

Title: PhD, Associate professor Position: Senior Lecturer, Chairman of Krefting Research Centre

Madeleine Rådinger graduated from the University of Gothenburg with an MSc degree in Molecular biology, and in2006 she received a PhD in Respiratory Medicine and Allergology at the University of Gothenburg. After her PhD, she took on a 2.5 years postdoctoral position at the Laboratory of Allergic Diseases, National Institute of Allergic and Infection Diseases, the National Institute of Health (NIH), in Bethesda, USA. She returned to the University of Gothenburg in 2010 and in 2013, she became Associate professor in Immunology.

Forskning

Rådinger research focuses on increasing the understanding of the immune systemin subgroups of asthma, including the contribution of immune regulatory microRNAs. The ultimate goal is to identify molecular drivers linked to clinical features in asthma subgroups, for stratification for targeted therapy, diagnosis and potentially identification of new therapeutic targets.

Her research is funded by the VBG group Herman Krefting Foundation for Asthma and Allergy Research, the Swedish Research Council, the Swedish Heart and Lung foundation, the Swedish Foundation for Strategic Research and ALF.

Rådinger collaborates with several national and international research groups studying immunology, respiratory research and microRNA biology. In 2019, she was awarded the big grant from the Swedish association for allergy research (SFFA) and the Swedish Cancer-and Allergy Foundation environmental medical award for her research.

Gruppmedlemmar

Artiklar

– 2019 års Miljömedicinska pris tilldelas Docent Madeleine Rådinger – Akademiliv - Madeleine Rådinger fick Svenska föreningen för Allergologis stora stipendium 2019

Utvalda publikationer

  1. Malmhäll C, Alawieh S, Lu Y, Sjöstrand M, Bossios A, Eldh M and Rådinger M. 2014. MicroRNA-155 is essential for TH2 mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immuol. 2014 May;133(5):1429-38. The first study to describe a role for microRNA-155 in the regulation of type 2 mediated allergic eosinophilic inflammation in a mouse model of asthma.
  2. Johansson K, Malmhäll C, Ramos-Ramirez P and Rådinger M. 2017. MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation. J Allergy Clin Immunol. 2017 Mar;139(3):1007-1016. This is the first study to describe a regulatory role for a microRNA in ILC2 functionality.
  3. Malmhäll C, Weidner J, Rådinger M. 2019. MicroRNA-155 expression suggests a sex disparity in innate lymphoid cells at the single-cell level. Cell Mol Immunol. 2019 Oct 10. doi: 10.1038/s41423-019-0303-4. The first study to describe that human circulating ILCs express microRNA-155 and that this expression is higher in females.