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- Albert Gyllencreutz Castellheim
Albert Gyllencreutz Castellheim
Senior Lecturer/ Chief Physician
Department of Anesthesiology and Intensive CareAbout Albert Gyllencreutz Castellheim
In 2012, I moved from Oslo to Gothenburg and entered my combination position which consists of 70% service as University Lecturer at University of Gothenburg and 30% service as senior consultant at Sahlgrenska University Hospital, Queen Silvia Children Hospital. A part of the University Lecturer position is to be a teacher in the university, and in my case a teacher for medical students and doctoral students. Another part of the position involves research.
Research:
In research, I have been the main supervisor of two doctoral students who have dissertated and assistant supervisor of another doctoral student who also has dissertated. I was also assistant supervisor to two doctoral students in the Faculty of Medicine, University of Oslo, but in connection with entering my position at Sahlgrenska Academy, handed over the responsibility to other research colleagues in University of Oslo. In Norway, my research included laboratory and experimental models of meconium aspiration syndrome and sepsis from an immunological perspective with focus on the complement system. After 2012, my main research focus became clinical trials in form of double blinded randomized controlled clinical trials in pediatric intensive care. In recent years and the coming years, there has been and will be a more emphasis on registry-based epidemiologic and outcome studies. Currently, I have two PhD-students who are working with their registry-based epidemiologic studies; one working with out of hospital cardiac arrest in children, and one with congenital heart diseases . My Pubmed publications give a thourough overview of my research fields and research activities.
My clinical workplace is the department of pediatric anesthesia and intensive care in Queen Silvia’s Children Hospital in Gothenburg. The department has a key role in the diagnosis and treatment of children with congenital heart disease. The hospital is one of two Swedish centers for the treatment of children with congenital heart disease, and therefore it is natural that the research projects in our department are closely linked to these children and other critically ill children who are treated in our hospital. Our research projects are interdisciplinary because the care of critically ill children is interdisciplinary. My research projects are currently focused on:
1) Epidemiology and outcomes in congenital heart disease (in collaboration with Register Center Västra Götaland)
2) Epidemiology and outcomes in out of hospital pediatric cardiac arrest (in collaboration with Register Center Västra Götaland)
3) Acute kidney injury postoperatively in children with congenital heart disease.
4) Neurodevelopmental problems after anesthesia surgery.
5) Inflammation in critical illness
Teaching:
I am a teacher in the course anesthesia and intensive care medicine which is currently a part of curriculum for the 8.th semester (of totally 11 semesters) in the medical education (Programme in Medicine) in Gothenburg. I have been deeply involved in planning, teaching and development of this course since 2014. The structure of Programme in Medicine will be changed nationwide in 2021, to what is called the New Programme in Medicine. In Gothenburg, in the New Programme in Medicine the course of anesthesia and intensive care medicine will be a part of 7th semester of totally 12 semesters.
Practical and hands-on training is of central importance in clinical medical education. The 8.th semester, the so called “surgery semester”, includes a one-day-simulating training with high fidelity mannequins. Currently, I have the responsibility for the simulation part of the course of anesthesia and intensive care medicine, and additionally coordinate the whole simulating part of 8th semester with the Simulatorcentrum i Väst.
I am also a teacher in the 10th semester in Programme in Medicine (Examensarbetet). The 10th semester is designated to in-depth scientific or developmental work. The teaching in this semester is project-based and individualized. The teachers usually have one or two students for the whole semester. For the spring semester 2023 I will have three 10th semester students.
Being a University Lecturer and a teacher means also being an examiner in basic and advanced level education (doctoral education). Accordingly, I am an examiner of medical students (8th and 10th semester) and PhD-students (half-time seminars and examining committees), as well as an examiner for the course Medical science for the residents (ST-läkare) in theRegion Västra Götaland.
As a University Lecturer one may contribute in designing and developing different university courses. For this reason, I had the shared responsibility for creating and developing the anesthesia and intensive care course in the following two programmes; 1) Complementary Programme for Physicians with Medical Degree from outside the EU/EES and Switzerland (2015-2018) and 2) Introduction course for newly arrived physicians (2016-2017). Furthermore, for a short period of time (2015-2016) I was a teacher in the course Inter-professional learning, which is a simulation-based course for medical students (11th semester) and nursing students (6th semester) where these two student groups commonly train in technical (medical) and non-technical (Crew Resource Management) aspects of caregiving.
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Chemical, biological and nerve gas attacks: need for education among healthcare personnel and medical students; a Swedish regional cross-sectional
web-survey.
Albert Gyllencreutz Castellheim, Gustav Persson, Juuso Kuikka, Karol Babinski, Yohan Robinson, Fabian Taube
BMC medical education - 2025 -
Persistent pro-inflammatory trait in elderly patients following treatment-resistant major depressive disorder: a longitudinal exploratory
study
Torfinn Lodoen Gaarden, Knut Engedal, Jurate Saltyte Benth, Marianne Larsen, Bernhard Lorentzen, Tom Eirik Mollnes, Tor Magne Bjolseth, Albert Gyllencreutz Castellheim
NORDIC JOURNAL OF PSYCHIATRY - 2024 -
Vi är redo – ge lärosätena en tydlig roll i
totalförsvaret
Yohan Robinson, Fabian Taube, Faraidoun Moradi, Albert Gyllencreutz Castellheim, Karen da Costa, Mats Isaksson, Jessica Alm, Filip Arnberg, Per Becker, Sofia Brorsson, Eric Carlström, Pär Daléus, Mats Eriksson, Maja Fjaestad, David Gisselsson Nord, Hedvig Glans, Caroline de Groot, Johanna Gustavsson, Helena Hervius Askling, Carl-Oscar Jonsson, Magnus Karlsson, Mats Koraeus, Aron Larsson, Kristina Lennquist Montán, Petter Ljungman, Björn Lund, Lovisa Lundholm, Jason Murphy, Christopher L. Rääf, Ritva Rosenbäck, Johan von Schreeb, Lisa Strömmer, Anton Westman, Kavot Zillén, Anna Zorzet, Mattias Öberg
Tidningen Curie - 2024 -
High-sensitive troponinT, interleukin-8, and interleukin-6 link with post-surgery risk in infant heart
surgery
Elin M. Thorlacius, Juho Keski-Nisula, Maria Vistnes, Tiina Ojala, Mattias Molin, Mats Synnergren, Birgitta S Romlin, Sven-Erik Ricksten, Håkan Wåhlander, Albert Gyllencreutz Castellheim
ACTA ANAESTHESIOLOGICA SCANDINAVICA - 2024 -
Out-of-Hospital Cardiac Arrest: Survival in Children and Young Adults over 30 years, a Nationwide Registry-Based Cohort
Study.
Hannah Fovaeus, Johan Holmén, Zacharias Mandalenakis, Johan Herlitz, Araz Rawshani, Albert Gyllencreutz Castellheim
Resuscitation - 2024 -
Survival Trends in Children With Tetralogy of Fallot in Sweden From 1970 to
2017.
Johanna Persson, Albert Gyllencreutz Castellheim, Mikael Dellborg, Kok Wai Giang, Christina Karazisi, Araz Rawshani, Zacharias Mandalenakis
JAMA network open - 2023 -
Outcome following anaesthesia in infancy in the Nordic countries: Subgroup analysis of the NECTARINE
study
T. G. Hansen, J. Vieri, W. B. Borke, Albert Castellheim
Acta Anaesthesiologica Scandinavica - 2023 -
Levosimendan Versus Milrinone and Release of Myocardial Biomarkers after Pediatric Cardiac Surgery: Post Hoc Analysis of Clinical Trial
Data
Elin M. Thorlacius, M. Vistnes, T. Ojala, J. Keski-Nisula, M. Molin, Birgitta S Romlin, M. Synnergren, Sven-Erik Ricksten, Håkan Wåhlander, Albert Castellheim
Pediatric Critical Care Medicine - 2021 -
Levosimendan Versus Milrinone for Inotropic Support in Pediatric Cardiac Surgery: Results From a Randomized
Trial.
Elin M. Thorlacius, Håkan Wåhlander, Tiina Ojala, Kaisa Ylänen, Juho Keski-Nisula, Mats J Synnergren, Birgitta Romlin, Sven-Erik Ricksten, Albert Castellheim
Journal of cardiothoracic and vascular anesthesia - 2020 -
Incidence of severe critical events in paediatric anaesthesia in Scandinavia: Secondary analysis of Anaesthesia PRactice In Children Observational Trial
(APRICOT)
T. G. Hansen, W. B. Borke, M. H. Isohanni, Albert Castellheim
Acta Anaesthesiologica Scandinavica - 2019 -
The Effect of Levosimendan Versus Milrinone on the Occurrence Rate of Acute Kidney Injury Following Congenital Heart Surgery in Infants: A Randomized Clinical
Trial.
Elin M. Thorlacius, Pertti K Suominen, Håkan Wåhlander, Juho Keski-Nisula, Maria Vistnes, Sven-Erik Ricksten, Mats J Synnergren, Birgitta S Romlin, Albert Castellheim
Pediatric critical care medicine - 2019 -
Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old
persons
T. L. Gaarden, K. Engedal, J. S. Benth, M. Larsen, B. Lorentzen, T. E. Mollnes, T. M. Bjolseth, Albert Castellheim
BMC Geriatr - 2018 -
Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration
Syndrome
A. M. Thomas, C. Schjalm, P. H. Nilsson, P. H. H. Lindenskov, R. Rortveit, R. Solberg, O. D. Saugstad, M. M. Berglund, P. Stromberg, C. Lau, T. Espevik, J. H. Jansen, Albert Castellheim, T. E. Mollnes, A. Barratt-Due
Neonatology - 2018 -
The role of general anesthesia on traits of neurodevelopmental disorders in a Swedish cohort of
twins.
Albert Castellheim, Sebastian Lundström, Mattias Molin, Ralf Kuja-Halkola, I Carina Gillberg, Christopher Gillberg
Journal of child psychology and psychiatry, and allied disciplines - 2018 -
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal
sepsis
B. C. Hellerud, H. L. Orrem, K. Dybwik, S. E. Pischke, A. Baratt-Due, Albert Castellheim, H. Fure, G. Bergseth, D. Christiansen, M. A. Nunn, T. Espevik, C. Lau, P. Brandtzaeg, E. W. Nielsen, T. E. Mollnes
Journal of Intensive Care - 2017 -
In vitro anti-platelet potency of ticagrelor in blood samples from infants and
children.
Fredrik Söderlund, Anna-Karin Asztély, Anders Jeppsson, Sven Nylander, Anders Berggren, Karin Nelander, Albert Castellheim, Birgitta S Romlin
Thrombosis research - 2015 -
Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential
therapies.
Paal Helge Haakonsen Lindenskov, Albert Castellheim, Ola Didrik Saugstad, Tom Eirik Mollnes
Neonatology - 2015 -
Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal
sepsis.
Bernt C Hellerud, Erik W Nielsen, Ebbe B Thorgersen, Julie K Lindstad, Anne Pharo, Tor I Tønnessen, Albert Castellheim, Tom E Mollnes, Petter Brandtzaeg
Critical care medicine - 2010 -
Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk
patients.
Albert Castellheim, Tom N Hoel, Vibeke Videm, Erik Fosse, Anne Pharo, Jan L Svennevig, Arnt E Fiane, Tom E Mollnes
The Annals of thoracic surgery - 2008 -
Complement activation reflects severity of meconium aspiration syndrome in newborn
pigs.
Paal H H Lindenskov, Albert Castellheim, Geir Aamodt, Ola D Saugstad, Tom E Mollnes
Pediatric research - 2004