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Anne Farewell
Senior Lecturer
Department of Chemistry & Molecular BiologyAbout Anne Farewell
Research Antibiotic resistance is quickly becoming a global crisis with bacterial resistance spreading worldwide. The research in my group previously focused on bacterial gene regulation in general but I have now decided to focus my efforts on the problem of antibiotic resistance. Specifically, we are studying which genes influence the spread of antibiotic resistance genes through conjugation (horizontal gene transfer) with the aim of inhibiting this process. We have teamed up with others at GU to utilize new tools to study this process and are part of the Centre for Antibiotic Resistance (CARe) at GU.
Education I was named Excellent Teacher at GU in 2015 for my commitment to and activities in education, educational research and resource design. I’m particularly interested in active learning and course design that integrates our work as researchers with our undergraduate education.
I am course leader for three courses as well as lecturer in others:
- BIO510 Prokaryotic Molecular Microbiology
- HPE102 Higher Education Teaching in Natural Sciences
- BIO001 The problem of antibiotic resistance
Outreach You can learn more about the problem of antibiotic resistance in an online course I have made available at www.antibiotic-resistance.org
I also maintain a Microbiology news Twitter and Facebook account: Twitter and Facebook
Committees and other Activities
Founder Gothenburg Women Scientists (gowosci.se) or on Facebook
Steering Group, Centre for Antibiotic Resistance Research (CARe)
Chairperson, Working Group on Gender Equality at Natural Sciences
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PCA, PC-CVA, and Random Forest of GCIB-SIMS Data for the Elucidation of Bacterial Envelope Differences in Antibiotic Resistance
Research
Alfred Fransson, Kelly Dimovska Nilsson, Alex Henderson, Anne Farewell, John S. Fletcher
ANALYTICAL CHEMISTRY - 2024 -
Discovery of novel inhibitors for Pseudomonas aeruginosa lipase enzyme from in silico and in vitro
studies
Asma Gholami, D. Minai-Tehrani, Anne Farewell, Leif A Eriksson
Journal of Biomolecular Structure & Dynamics - 2024 -
Scaling-up the biodiversity-ecosystem functioning relationship: the effect of environmental heterogeneity on transgressive
overyielding
Lars Gamfeldt, James Hagan, Anne Farewell, Martin Palm, Jonas Warringer, Fabian Roger
Oikos - 2023 -
Effect of anode material and dispersal limitation on the performance and biofilm community in microbial electrolysis
cells
Marie Abadikhah, Ming Liu, Frank Persson, Britt Marie Wilén, Anne Farewell, Jie Sun, Oskar Modin
Biofilm - 2023 -
Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and
SARS-CoV-2
Kyong-Su Park, Kristina Svennerholm, Rossella Crescitelli, Cecilia Lässer, Inta Gribonika, Mickael Andersson, Jonas Boström, Hanna Alalam, Ali M Harandi, Anne Farewell, Jan Lötvall
Journal of Nanobiotechnology - 2023 -
Evidence of competition between electrogens shaping electroactive microbial communities in microbial electrolysis
cells
Marie Abadikhah, Miguel de Celis Rodriguez, Frank Persson, Britt Marie Wilén, Anne Farewell, Oskar Modin
Frontiers in Microbiology - 2022 -
Development of Dicationic Bisguanidine-Arylfuran Derivatives as Potent Agents against Gram-Negative
Bacteria.
Catarina Bourgard, Diego Rodríguez-Hernández, Anastasia Rudenko, Carolin Rutgersson, Martin Palm, D. G. Joakim Larsson, Anne Farewell, Morten Grøtli, Per Sunnerhagen
Antibiotics - 2022 -
The Effect of Heavy Metals on Conjugation Efficiency of an F-Plasmid in Escherichia
coli.
Martin Palm, Alfred Fransson, Julia Hultén, Karolina Búcaro Stenman, Amina Allouche, Oscar E Chiang, Mirthe L Constandse, Karlijn J van Dijk, Suheda Icli, Bela Klimesova, Emma Korhonen, Gema Martínez-Crespo, Dominik Meggers, Margarita Naydenova, Maria An Polychronopoulou, Dominik B Schuntermann, Havva Unal, Agnieszka Wasylkowska, Anne Farewell
Antibiotics (Basel, Switzerland) - 2022 -
Conjugative transfer of multi-drug resistance IncN plasmids from environmental waterborne bacteria to Escherichia
coli
J. Guzman-Otazo, E. Joffre, J. Agramont, N. Mamani, Jekaterina Jutkina, F. Boulund, Y. O. O. Hu, Daphne Jumilla-Lorenz, Anne Farewell, D. G. Joakim Larsson, Carl-Fredrik Flach, V. Iniguez, Åsa Sjöling
Frontiers in Microbiology - 2022 -
Genome-Wide Association Study Reveals Host Factors Affecting Conjugation in Escherichia
coli
L. Van Wonterghem, M. De Chiara, G. Liti, Jonas Warringer, Anne Farewell, N. Verstraeten, J. Michiels
Microorganisms - 2022 -
Machine Learning Prediction of Resistance to Subinhibitory Antimicrobial Concentrations from Escherichia coli
Genomes.
Sam Benkwitz-Bedford, Martin Palm, Talip Yasir Demirtas, Ville Mustonen, Anne Farewell, Jonas Warringer, Leopold Parts, Danesh Moradigaravand
mSystems - 2021 -
Interrogation of chemical changes on, and through, the bacterial envelope of Escherichia coli FabF mutant using time-of-flight secondary ion mass
spectrometry
Kelly Dimovska Nilsson, Johan Grandén, Anne Farewell, John S. Fletcher
Surface and Interface Analysis - 2021 -
Genomic Epidemiology and Evolution of Escherichia coli in Wild Animals in
Mexico
R. Murphy, Martin Palm, V. Mustonen, Jonas Warringer, Anne Farewell, L. Parts, D. Moradigaravand
mSphere - 2021 -
Antibacterial activity of 2-amino-3-cyanopyridine
derivatives
Ibrahim Mamedov, Farid Naghiyev, Abel Maharramov, Owens Uwangue, Anne Farewell, Per Sunnerhagen, Mate Erdelyi
Mendeleev Communications - 2020 -
A High-Throughput Method for Screening for Genes Controlling Bacterial Conjugation of Antibiotic
Resistance.
Hanna Alalam, Fabrice Graf, Martin Palm, Marie Abadikhah, Martin Zackrisson, Jonas Boström, Alfred Fransson, Chris Hadjineophytou, Linnéa Persson, Simon Stenberg, Matilda Mattsson, Payam Ghiaci, Per Sunnerhagen, Jonas Warringer, Anne Farewell
mSystems - 2020 -
Increased antibiotic efficacy and noninvasive monitoring of Staphylococcus epidermidis biofilms using per-cysteamine-substituted γ-cyclodextrin - A delivery effect validated by fluorescence
microscopy.
Hanna Thomsen, Marco Agnes, Owens Uwangue, Linnèa Persson, Matilda Mattsson, Fabrice Graf, Eleni-Marina Kasimati, Konstantina Yannakopoulou, Marica B Ericson, Anne Farewell
International journal of pharmaceutics - 2020 -
Teaching about antibiotic resistance to a broad audience: a multidisciplinary
approach.
Kristian Kvint, Martin Palm, Anne Farewell
FEMS microbiology letters - 2020 -
Chemical Changes On, and Through, The Bacterial Envelope in Escherichia coli Mutants Exhibiting Impaired Plasmid Transfer Identified Using Time-of-Flight Secondary Ion Mass
Spectrometry.
Kelly Dimovska Nilsson, Martin Palm, James Hood, Jake Sheriff, Anne Farewell, John S. Fletcher
Analytical chemistry - 2019 -
Inhibiting conjugation as a tool in the fight against antibiotic
resistance
Fabrice Graf, Martin Palm, Jonas Warringer, Anne Farewell
Drug Development Research - 2019 -
High throughput screening of growth on sub-MIC antibiotics and conjugation efficiency of a collection of natural E. coli
isolates
Martin Palm, Fabrice Graf, Owens Uwangue, Marta Tous Mohedano, Daniel Jaén-Luchoro, Edward R.B. Moore, Jonas Warringer, Anne Farewell
International Symposium of the International Society for Plasmid Biology and other Mobile Genetic Elements - 2018 -
Spatially confined photoinactivation of bacteria: Towards novel tools for detailed mechanistic
studies
Hanna Thomsen, Jeemol James, Anne Farewell, Marica B Ericson
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Multiphoton Microscopy in the Biomedical Sciences XVIII 2018; San Francisco; United States; 28 January 2018 through 30 January 2018. Vol 10498 - 2018 -
Exploring photoinactivation of microbial biofilms using laser scanning microscopy and confined two-photon
excitation.
Hanna Thomsen, Fabrice Graf, Anne Farewell, Marica B Ericson
Journal of biophotonics - 2018 -
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+
site.
Weixiao Yuan Wahlgren, Elin Dunevall, Rachel A North, Aviv Paz, Mariafrancesca Scalise, Paola Bisignano, Johan Bengtsson-Palme, Parveen Goyal, Elin Claesson, Rhawnie Caing Carlsson, Rebecka Andersson, Konstantinos Beis, Ulf J Nilsson, Anne Farewell, Lorena Pochini, Cesare Indiveri, Michael Grabe, Renwick C J Dobson, Jeff Abramson, S Ramaswamy, Rosmarie Friemann
Nature Communications - 2018 -
Rising to the Top: Promoting Deeper Learning in the
Laboratory
Anne Farewell
National Center for Case Study Teaching in Science - 2018 -
Horizontal transmission factors spreading antibiotic
resistance
Fabrice Graf, Hanna Alalam, Martin Zackrisson, Martin Palm, Payam Ghiaci, Per Sunnerhagen, Jonas Warringer, Anne Farewell
International Symposium of the International Society for Plasmid Biology and other Mobile Genetic Elements - 2018 -
Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome
data.
Danesh Moradigaravand, Martin Palm, Anne Farewell, Ville Mustonen, Jonas Warringer, Leopold Parts
PLoS computational biology - 2018 -
Conjugation factors controlling F-plasmid antibiotic resistance
transmission
Hanna Alalam, Fabrice Graf, Martin Palm, Marie Abadikhah, Martin Zackrisson, Matilda Mattsson, Chris Hadjineophytou, Linnèa Persson, Simon Stenberg, Payam Ghiaci, Per Sunnerhagen, Jonas Warringer, Anne Farewell
BioRxiv - 2018 -
Horizontal transmission factors spreading antibiotic
resistance
Fabrice Graf, Hanna Alalam, Martin Zackrisson, Per Sunnerhagen, Jonas Warringer, Anne Farewell
7th Congress of European Microbiologists (FEMS 2017) - 2017 -
Delivery of cyclodextrin polymers to bacterial biofilms - An exploratory study using rhodamine labelled cyclodextrins and multiphoton
microscopy
Hanna Thomsen, Gábor Benkovics, Éva Fenyvesi, Anne Farewell, Milo Malanga, Marica B Ericson
International Journal of Pharmaceutics - 2017 -
Investigating the Role of the Stringent Response in Lipid Modifications during the Stationary Phase in E. coli by Direct Analysis with Time-of-Flight-Secondary Ion Mass
Spectrometry
Patrick M. Wehrli, Tina B. Angerer, Anne Farewell, John S. Fletcher, Johan Gottfries
Analytical Chemistry - 2016 -
Teaching Science: Design of a Master’s Level Biology
Course
Anne Farewell
Pedagogical Essays, The unit for Pedagogical Development and Interactive Learning (PIL) - 2015 -
The potential improvement of team-working skills in Biomedical and Natural Science students using a problem-based learning
approach.
Anne Farewell, Forough Nowrouzian
Journal of Problem Based Learning in Higher Education - 2013 -
UspB, a member of the sigma-S regulon, facilitates RuvC resolvase
function.
Örjan Persson, Thomas Nyström, Anne Farewell
DNA repair - 2010 -
Increased RNA polymerase availability directs resources towards growth at the expense of
maintenance.
Bertil Gummesson, Lisa U. Magnusson, Martin Lovmar, Kristian Kvint, Örjan Persson, Manuel Ballesteros, Anne Farewell, Thomas Nyström
The EMBO journal - 2009 -
The tumor suppressor homolog in fission yeast, myh1+, displays a strong interaction with the checkpoint gene
rad1+
Kristina Jansson, Jonas Warringer, Anne Farewell, Han-Oh Park, Kwang-Lae Hoe, Dong-Uk Kim, Jacqueline Hayles, Per Sunnerhagen
Mutation Research - 2008 -
Metabolic control of the Escherichia coli universal stress protein response through
fructose-6-phosphate
Örjan Persson, Åsa Valadi, Thomas Nyström, Anne Farewell
MOLECULAR MICROBIOLOGY - 2007 -
Identical, independent, and opposing roles of ppGpp and DksA in Escherichia
coli.
Lisa U. Magnusson, Bertil Gummesson, Predrag Joksimovic, Anne Farewell, Thomas Nyström
Journal of bacteriology - 2007 -
ppGpp: a global regulator in Escherichia
coli
Lisa U. Magnusson, Anne Farewell, Thomas Nyström
TRENDS in Microbiology - 2005 -
Heat shock protein-mediated resistance to high hydrostatic pressure in Escherichia
coli
A. Aertsen, K. Vanoirbeek, P. De Spiegeleer, J. Sermon, K. Hauben, Anne Farewell, Thomas Nyström, C. W. Michiels
Applied and Environmental Microbiology - 2004 -
Deficiencies in the endoplasmic reticulum (ER)-membrane protein Gab1p perturb transfer of glycosylphosphatidylinositol to proteins and cause perinuclear ER-associated actin bar
formation
Stephen J. Grimme, Xiang-Dong Gao, Paul S. Martin, Kim Tu, Serguei E. Tcheperegine, Kathleen Corrado, Anne Farewell, Peter Orlean, Erfei Bi
MOLECULAR BIOLOGY OF THE CELL - 2004 -
Underproduction of sigma 70 mimics a stringent response. A proteome
approach.
Lisa U. Magnusson, Thomas Nyström, Anne Farewell
The Journal of biological chemistry - 2003 -
Fed-batch production of recombinant beta-galactosidase using the universal stress promoters uspA and uspB in high cell density
cultivations.
Ingela Prytz, Anna Maria Sandén, Thomas Nyström, Anne Farewell, Asa Wahlström, Cecilia Förberg, Zoltan Pragai, Mike Barer, Colin Harwood, Gen Larsson
Biotechnology and bioengineering - 2003