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Mikael Alsterholm
Affiliated to Research
Department of Dermatology and VenereologyAbout Mikael Alsterholm
Mikael Alsterholm is a senior consultant in dermatology and venereology and a postdoctoral researcher with a PhD in Medical Science. He has been section manager at the clinical department of dermatology and venereology at Sahlgrenska University Hospital during 2011-2023.
He is a member of the steering group for SwedAD – the Swedish nation-wide quality registry for atopic dermatitis.
Research focus area
Mikael Alsterholm's research focuses on different aspects of treatment and follow-up of atopic dermatitis (eczema).
Atopic dermatitis affects 20% of children and 10% of adults living in Sweden and the prevalence is similar in other parts of the world. Individuals with atopic dermatitis suffer greatly from itch, sleep disturbance, and skin lesions that affect social interaction and quality of life. In recent years new systemic pharmacotherapies for atopic dermatitis have been introduced. These new treatments can be very effective but real-world data is still limited. To improve health-related quality of life for the large group of patients with atopic dermatitis it is important to investigate the effect and safety of new and conventional therapies, predictors of efficacy, and patients´ perception and experience of these therapies.
Mikael Alsterholm's current work includes registry-based studies of the outcome of systemic treatment for atopic dermatitis, clinical interventional studies on the effect of phototherapy on vitamin D metabolism in atopic dermatitis, and a digital questionnaire study on patients’ experiences of side effects of treatment with topical corticosteroids. The work is done in collaboration with researchers at Karolinska Institutet, Linköping University, Umeå University and in the steering group for SwedAD.
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The Effect of Phototherapy on Systemic Inflammation Measured with Serum Vitamin D-Binding Protein and hsCRP in Patients with Inflammatory Skin
Disease
Andrea Elmelid, Maria Siekkeri Vandikas, Martin Gillstedt, Mikael Alsterholm, Amra Osmancevic
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
A systematic review investigating the proportion of clinical images shared in prospective randomized controlled trials involving patients with atopic dermatitis and systemic
pharmacotherapy
Sam Polesie, Mikael Alsterholm
Journal of dermatological treatment - 2024 -
Cross-Cultural Validation of the RECAP of Atopic Eczema Question-naire in a Swedish
Population
Gunnthorunn Sigurdardottir, Mikael Alsterholm, Chris D. Andersson, Maria Bradley, Mari Helen Sandström Falk, Emma K. Johansson, Maria Lundqvist, Andreas Sonesson, Åke Svensson, Grigorios Theodosiou, Sophie Vrang, Laura B. Von Kobyletzki
Acta Dermato-Venereologica - 2024 -
The Effect of Narrow-Band Ultraviolet B Phototherapy on Free and Total Vitamin D Serum Levels in Mild to Severe Plaque
Psoriasis
Andrea Elmelid, Maria Siekkeri Vandikas, Martin Gillstedt, Amra Osmancevic, Mikael Alsterholm
Biomolecules - 2023 -
Establishment and Utility of SwedAD: A Nationwide Swedish Registry for Patients with Atopic Dermatitis Receiving Systemic
Pharmacotherapy
Mikael Alsterholm, Axel Svedbom, Chris D. Anderson, Lena Holm Sommar, Lina U. Ivert, Anna Josefson, Laura Von Kobyletzki, Magnus Lindberg, Lena Lundeberg, Maria Lundqvist, Elisabet Nylander, Mari Helen Sandström Falk, Alexander Shayesteh, Gunnthorunn Sigurdardottir, Andreas Sonesson, Åke Svensson, Marie Virtanen, Sophie Vrang, Carl Fredrik Wahlgren, Maria Bradley, Emma K. Johansson
Acta dermato-venereologica - 2023 -
Effects of Phototherapy on Free Vitamin D Levels in Ten Patients with Atopic
Dermatitis
Andrea Elmelid, Amra Osmancevic, Martin Gillstedt, Mikael Alsterholm
International Journal of Translational Medicine - 2022 -
Granulomatous mycosis fungoides, with features of granulomatous slack skin. Co-morbidity with several visceral cancers, indolent course of the skin disease. Disparity of clinical picture and
histopathology
Annica Inerot, Mikael Alsterholm
European Journal of Cancer Supplement 1, September 2018, Pages S23-S24 - 2018 -
A simple skin blister technique for the study of in vivo transmigration of human
leukocytes.
Lisa Davidsson, Lena Björkman, Karin Christenson, Mikael Alsterholm, Charlotta Movitz, Fredrik Bergh Thorén, Anna Karlsson, Amanda Welin, Johan Bylund
Journal of immunological methods - 2013 -
Human NK Cells induce neutrophil apoptosis via an NKp46- and Fas-dependent
mechanism.
Fredrik Bergh Thorén, Rebecca E Riise, Jenny Ousbäck, Mariella Della Chiesa, Mikael Alsterholm, Emanuela Marcenaro, Silvia Pesce, Carola Prato, Claudia Cantoni, Johan Bylund, Lorenzo Moretta, Alessandro Moretta
Journal of immunology (Baltimore, Md. : 1950) - 2012 -
Studies on colonization and infection with Staphylococcus aureus and other microbes in skin
disease
Mikael Alsterholm
2012 -
Antimicrobial activity of topical skin pharmaceuticals - an in vitro
study
Mikael Alsterholm, Nahid Karami, Jan Faergemann
Acta Dermato-Venereologica - 2010 -
Fusidic acid-resistant Staphylococcus aureus in impetigo contagiosa and secondarily infected atopic
dermatitis.
Mikael Alsterholm, Ingela Flytström, Ing-Marie Bergbrant, Jan Faergemann
Acta dermato-venereologica - 2010 -
In vitro activity of chlorhexidine and pentane-1,5-diol and their combination on Candida albicans, Staphylococcus aureus and Propionibacterium
acnes.
Nahid Karami, Mikael Alsterholm, Jan Faergemann
Acta dermato-venereologica - 2009 -
Frequency of bacteria, Candida and malassezia species in
balanoposthitis.
Mikael Alsterholm, Ingela Flytström, Ragna Leifsdottir, Jan Faergemann, Ing-Marie Bergbrant
Acta dermato-venereologica - 2008 -
PPARalpha deficiency increases secretion and serum levels of apolipoprotein B-containing
lipoproteins.
D Lindén, Mikael Alsterholm, H Wennbo, J Oscarsson
Journal of lipid research - 2001