- Home
- About
- Find staff
- Yvonne Wettergren
Yvonne Wettergren
Affiliated to Research
Department of Surgery-
A New IL-6-Inducing Mechanism in Cancer with New Therapeutic
Possibilities
Leif Hakansson, Pontus Duner, Erik Brostromer, Bengt Gustavsson, Yvonne Wettergren, Bijar Ghafouri, Annika Hakansson, Birgitta Clinchy
CANCERS - 2024 -
Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression
Patterns
Maria K Magnusson, Anna Bas-Forsberg, Alexandra Verveda, Maria Sapnara, Julie Lorent, Otto Savolainen, Yvonne Wettergren, Hans Strid, Magnus Simrén, Lena Öhman
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and
function
William Rodin, Louis Szeponik, Tsvetanka Rangelova, Firaol Tamiru Kebede, Tobias Österlund, Patrik Sundström, Stephen Hogg, Yvonne Wettergren, Antonio Cosma, Anders Ståhlberg, Elinor Bexe-Lindskog, Marianne Quiding-Järbrink
CANCER IMMUNOLOGY IMMUNOTHERAPY - 2024 -
Epigenetic differences in the tumor suppressor genes MLH1 and p16INK4a between Nepalese and Swedish patients with colorectal
cancer
Bikal Ghimire, Göran Kurlberg, Peter Falk, Yogendra Singh, Yvonne Wettergren
INNOVATIVE SURGICAL SCIENCES - 2024 -
Assessment of bacterial and viral gut communities in healthy and tumoral colorectal tissue using RNA and DNA deep
sequencing
Ainhoa Garcia-Serrano, Dhananjay Mukhedkar, Emilie Hultin, Ulla Rudsander, Yvonne Wettergren, Agustín Enrique Ure, Joakim Dillner, Laila Sara Arroyo-Mühr
Cancer Medicine - 2023 -
Immune Microenvironment in Sporadic Early-Onset versus Average-Onset Colorectal
Cancer
Fanny Andric, Ala Al-Fairouzi, Yvonne Wettergren, Louis Szeponik, Elinor Bexe-Lindskog, J. C. Cusack, G. Tumusiime, Marianne Quiding-Järbrink, David Ljungman
Cancers - 2023 -
Impact of thymidine phosphorylase and CD163 expression on prognosis in stage II colorectal
cancer
Donia Kaidi, Louis Szeponik, Ulf Yrlid, Yvonne Wettergren, Elinor Bexe-Lindskog
Clinical & Translational Oncology - 2022 -
Increasing Dosage of Leucovorin Results in Pharmacokinetic and Gene Expression Differences When Administered as Two-Hour Infusion or Bolus Injection to Patients with Colon
Cancer
Helena Taflin, Elisabeth Odin, Göran Carlsson, Bengt Gustavsson, Yvonne Wettergren, Elinor Bexe-Lindskog
Cancers - 2022 -
Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and
Colonoids
Luiza Moraes Holst, Cristina Iribarren, Maria Sapnara, O. Savolainen, Hans Törnblom, Yvonne Wettergren, H. Strid, Magnus Simrén, Maria K Magnusson, Lena Öhman
International Journal of Molecular Sciences - 2022 -
Inflammation suppresses DLG2 expression decreasing inflammasome
formation
S. Keane, M. Herring, P. Rolny, Yvonne Wettergren, K. Ejeskar
Journal of Cancer Research and Clinical Oncology - 2022 -
Patient-derived scaffolds as a model of colorectal
cancer
Gabrielle T. Parkinson, Simona Salerno, Parmida Ranji, Joakim Håkansson, Y. Bogestal, Yvonne Wettergren, Anders Ståhlberg, Elinor Bexe-Lindskog, Göran Landberg
Cancer Medicine - 2021 -
Exhaustion in tumor-infiltrating Mucosal-Associated Invariant T (MAIT) cells from colon cancer
patients
William Rodin, Patrik Sundström, Filip Ahlmanner, Louis Szeponik, Kamil Kajetan Zajt, Yvonne Wettergren, Elinor Bexe-Lindskog, Marianne Quiding Järbrink
Cancer Immunology Immunotherapy - 2021 -
Plasma deoxyuridine as a surrogate marker for toxicity and early clinical response in patients with metastatic colorectal cancer after 5-FU-based therapy in combination with
arfolitixorin
Helena Taflin, Elisabeth Odin, Göran Carlsson, R. Tell, Bengt Gustavsson, Yvonne Wettergren
Cancer Chemotherapy and Pharmacology - 2021 -
Antigen Presenting Cells from Tumor and Colon of Colorectal Cancer Patients Are Distinct in Activation and Functional Status, but Comparably Responsive to Activated T
Cells.
Frank Liang, Azar Rezapour, Louis Szeponik, Samuel Alsén, Yvonne Wettergren, Elinor Bexe-Lindskog, Marianne Quiding-Järbrink, Ulf Yrlid
Cancers - 2021 -
Intratumoral regulatory T cells from colon cancer patients comprise several activated effector
populations
Louis Szeponik, Filip Ahlmanner, Patrik Sundström, William Rodin, Bengt Gustavsson, Elinor Bexe-Lindskog, Yvonne Wettergren, Marianne Quiding-Järbrink
Bmc Immunology - 2021 -
Pharmacokinetics of preoperative intraperitoneal 5-FU in patients with pancreatic ductal
adenocarcinoma
M. Oman, Yvonne Wettergren, Elisabeth Odin, S. Westermark, Peter Naredi, O. Hemmingsson, Helena Taflin
Cancer Chemotherapy and Pharmacology - 2021 -
Association of DNA repair gene variants with colorectal cancer: risk, toxicity, and
survival
Hamideh Salimzadeh, Elinor Bexe-Lindskog, Bengt Gustavsson, Yvonne Wettergren, David Ljungman
Bmc Cancer - 2020 -
Folate pathway genes linked to mitochondrial biogenesis and respiration are associated with outcome of patients with stage III colorectal
cancer
Elisabeth Odin, Arvid Sondén, Göran Carlsson, Bengt Gustavsson, Yvonne Wettergren
Tumor Biology - 2019 -
Hepatic deletion of p110? and p85? results in insulin resistance despite sustained IRS1-associated phosphatidylinositol kinase
activity
Victoria Rotter Sopasakis, Aditi Chaudhari, Katarina Ejeskär, Yvonne Wettergren, C. Ronald Kahn
F1000Research - 2018 -
Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk
loci
T. Tanskanen, L. van den Berg, N. Valimaki, M. Aavikko, E. Ness-Jensen, K. Hveem, Yvonne Wettergren, Elinor Bexe-Lindskog, N. Tonisson, A. Metspalu, K. Silander, G. Orlando, P. J. Law, S. Tuupanen, A. E. Gylfe, U. A. Hanninen, T. Cajuso, J. Kondelin, A. P. Sarin, E. Pukkala, P. Jousilahti, V. Salomaa, S. Ripatti, A. Palotie, H. Jarvinen, L. Renkonen-Sinisalo, A. Lepisto, J. Bohm, J. P. Mecklin, N. A. Al-Tassan, C. Palles, L. Martin, E. Barclay, A. Tenesa, S. M. Farrington, M. N. Timofeeva, B. F. Meyer, S. M. Wakil, H. Campbell, C. G. Smith, S. Idziaszczyk, T. S. Maughan, R. Kaplan, R. Kerr, D. Kerr, D. D. Buchanan, A. K. Win, J. Hopper, M. A. Jenkins, P. A. Newcomb, S. Gallinger, D. Conti, F. R. Schumacher, G. Casey, J. P. Cheadle, M. G. Dunlop, I. P. Tomlinson, R. S. Houlston, K. Palin, L. A. Aaltonen
International Journal of Cancer - 2018 -
Comparison of Stage and Lymph Node Ratio in Young and Older Patients with Colorectal Cancer Operated in a Tertiary Hospital in
Nepal.
Bikal Ghimire, Yogendra Prasad Singh, Göran Kurlberg, Yvonne Wettergren
Journal of Nepal Health Research Council - 2018 -
Relationship between folate concentration and expression of folate-associated genes in tissue and plasma after intraoperative administration of leucovorin in patients with colorectal
cancer
Helena Taflin, Elisabeth Odin, Kristoffer Derwinger, Göran Carlsson, Bengt Gustavsson, Yvonne Wettergren
Cancer Chemotherapy and Pharmacology - 2018 -
Methodological development and biological observations of cell free DNA with a simple direct fluorescent assay in colorectal
cancer.
A K Boysen, B S Sørensen, A C Lefevre, R Abrantes, J S Johansen, B V Jensen, J V Schou, F O Larsen, D Nielsen, H Taflin, B Gustavson, Yvonne Wettergren, B S Sorensen, A H Ree, S Dueland, N Pallisgaard, K L Spindler
Clinica chimica acta; international journal of clinical chemistry - 2018 -
Intestinal microbiota is altered in patients with colon cancer and modified by probiotic
intervention
A. A. Hibberd, A. Lyra, A. C. Ouwehand, Peter Rolny, Helena Lindegren, Lennart Cedgård, Yvonne Wettergren
Bmj Open Gastroenterology - 2017 -
DNA alterations in Cd133+ and Cd133- tumour cells enriched from intra-operative human colon tumour
biopsies.
Diana Lizeth Cervantes-Madrid, Yvonne Wettergren, Peter Falk, Kent Lundholm, Annika Gustafsson Asting
BMC cancer - 2017 -
AGXT and ERCC2 polymorphisms are associated with clinical outcome in metastatic colorectal cancer patients treated with
5-FU/oxaliplatin.
J B Kjersem, M Thomsen, T Guren, J Hamfjord, Göran Carlsson, Bengt Gustavsson, T Ikdahl, G Indrebø, P Pfeiffer, O Lingjærde, K M Tveit, Yvonne Wettergren, E H Kure
The pharmacogenomics journal - 2016 -
p110alpha hot spot mutations E545K and H1047R exert metabolic reprogramming independently of p110alpha kinase
activity
Aditi Chaudhari, Daniel Krumlinde, Annika Lundqvist, Levent Akyürek, Sashidar Bandaru, Kristina Skålen, Marcus Ståhlman, Jan Borén, Yvonne Wettergren, Katarina Ejeskär, Victoria Rotter Sopasakis
Molecular and Cellular Biology - 2015 -
The Proportion of Diploid 46,XX Cells Increases with Time in Women with Turner Syndrome-A 10-Year Follow-Up
Study
Anna-Maria Denes, Kerstin Landin-Wilhelmsen, Yvonne Wettergren, Inger Bryman, Charles Hanson
Genetic Testing and Molecular Biomarkers - 2015 -
Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status following Adjuvant Bolus 5-FU-Based
Chemotherapy.
Elisabeth Odin, Arvid Sondén, Bengt Gustavsson, Göran Carlsson, Yvonne Wettergren
Molecular medicine (Cambridge, Mass.) - 2015 -
The Unique Non-Catalytic C-Terminus of P37delta-PI3K Adds Proliferative Properties In Vitro and In
Vivo
Katarina Ejeskär, O. Vickes, A. Kuchipudi, Yvonne Wettergren, Anne Uv, Victoria Rotter Sopasakis
Plos One - 2015 -
A pharmacokinetic and pharmacodynamic investigation of Modufolin(®) compared to Isovorin (®) after single dose intravenous administration to patients with colon cancer: a randomized
study.
Yvonne Wettergren, Helena Taflin, Elisabeth Odin, Karl Kodeda, Kristoffer Derwinger
Cancer chemotherapy and pharmacology - 2015 -
A population-based cohort study on adherence to practice guidelines for adjuvant chemotherapy in colorectal
cancer.
Elinor Bexe-Lindskog, Katrín Asta Gunnarsdóttir, Kristoffer Derwinger, Yvonne Wettergren, Bengt Glimelius, Karl Kodeda
BMC cancer - 2014 -
Folate levels measured by LC-MS/MS in patients with colorectal cancer treated with different leucovorin
dosages.
Helena Taflin, Yvonne Wettergren, Elisabeth Odin, Kristoffer Derwinger
Cancer chemotherapy and pharmacology - 2014 -
Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal
cancer.
Elinor Bexe-Lindskog, Kristoffer Derwinger, Bengt Gustavsson, Peter Falk, Yvonne Wettergren
BMC clinical pathology - 2014 -
Pretherapeutic uracil and dihydrouracil levels in saliva of colorectal cancer patients are associated with toxicity during adjuvant 5-fluorouracil-based
chemotherapy.
Göran Carlsson, Elisabeth Odin, Bengt Gustavsson, Yvonne Wettergren
Cancer chemotherapy and pharmacology - 2014 -
Folate Levels and Polymorphisms in the Genes MTHFR, MTR, and TS in Colorectal
Cancer.
Helena Taflin, Yvonne Wettergren, Elisabeth Odin, Göran Carlsson, Kristoffer Derwinger
Clinical Medicine Insights. Oncology - 2014 -
Changes in thymidine phosphorylase gene expression related to treatment of rectal
cancer.
Kristoffer Derwinger, Elinor Bexe-Lindskog, Erik Palmqvist, Yvonne Wettergren
Anticancer research - 2013 -
Determination of reduced folates in tumor and adjacent mucosa of colorectal cancer patients using
LC-MS/MS.
Elisabeth Odin, Yvonne Wettergren, Göran Carlsson, Bengt Gustavsson
Biomedical chromatography : BMC - 2013 -
Pretherapeutic uracil and dihydrouracil levels of colorectal cancer patients are associated with sex and toxic side effects during adjuvant 5-flurorouracil-based
chemotherapy.
Yvonne Wettergren, Göran Carlsson, Elisabeth Odin, Bengt Gustavsson
Cancer - 2012 -
p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in
tumors.
Susanne Fransson, Anne Uv, Henry Eriksson, Mattias K Andersson, Yvonne Wettergren, Martin Bergö, Katarina Ejeskär
Oncogene - 2012 -
Comparison of bacterial quantities in left and right colon biopsies and
faeces.
Anna Lyra, Sofia Forssten, Peter Rolny, Yvonne Wettergren, Sampo J Lahtinen, Krista Salli, Lennart Cedgård, Elisabeth Odin, Bengt Gustavsson, Arthur C Ouwehand
World journal of gastroenterology : WJG - 2012 -
Thymidine Phosphorylase Gene Expression in Stage III Colorectal
Cancer.
Elinor Bexe-Lindskog, Yvonne Wettergren, Elisabeth Odin, Bengt Gustavsson, Kristoffer Derwinger
Clinical Medicine Insights. Oncology - 2012 -
Genomic CGH-assessed structural DNA alterations in rectal carcinoma as related to local recurrence following primary operation for
cure.
Karl Kodeda, Annika Gustafsson Asting, Christina Lönnroth, Kristoffer Derwinger, Yvonne Wettergren, Svante Nordgren, Bengt Gustavsson, Kent Lundholm
International journal of oncology - 2012 -
Gene Polymorphisms MTHFRC677T and MTRA2756G as Predictive Factors in Adjuvant Chemotherapy for Stage III Colorectal
Cancer.
Helena Taflin, Yvonne Wettergren, Elisabeth Odin, Göran Carlsson, Kristoffer Derwinger
Anticancer research - 2011 -
Polymorfier i genen för methionin syntas påverkar risken för biverkningar vid adjuvant cytostatika behandling av kolorektal
cancer
Helena Taflin, Yvonne Wettergren, Bengt Gustavsson, Kristoffer Derwinger
Svensk Kirurgisk Förening - 2010 -
MTHFR, MTR, and MTRR Polymorphisms in Relation to p16INK4A Hypermethylation in Mucosa of Patients with Colorectal
Cancer.
Yvonne Wettergren, Elisabeth Odin, Göran Carlsson, Bengt Gustavsson
Molecular medicine - 2010 -
Tymidinfosforylas, en prediktiv markör för 5-FU-baserad cytostatikabehandling vid kolorektal
cancer
Elinor Bexe-Lindskog, Yvonne Wettergren, Kristoffer Derwinger, Bengt Gustavsson
Svensk Kirurgisk Förening - 2010 -
Molecular determinants of efficacy for 5-FU-based treatments in advanced colorectal cancer: MRNA expression for 18 chemotherapy-related
genes
Bengt Gustavsson, Christopher Kaiser, Göran Carlsson, Yvonne Wettergren, Elisabeth Odin, Elinor Bexe-Lindskog, Clet Niyikiza, Ma Doreen
International Journal of Cancer - 2009 -
A study of the MTHFR gene polymorphism C677T in colorectal
cancer.
Kristoffer Derwinger, Yvonne Wettergren, Elisabeth Odin, Göran Carlsson, Bengt Gustavsson
Clinical colorectal cancer - 2009 -
Molecular determinants of efficacy for 5-FU-based treatments in advanced colorectal cancer: mRNA expression for 18 chemotherapy-related
genes.
Bengt Gustavsson, Christopher Kaiser, Göran Carlsson, Yvonne Wettergren, Elisabeth Odin, Elinor Bexe-Lindskog, Clet Niyikiza, Doreen Ma
International journal of cancer. Journal international du cancer - 2009 -
p16(INK4a) Gene Promoter Hypermethylation in Mucosa as a Prognostic Factor for Patients with Colorectal
Cancer.
Yvonne Wettergren, Elisabeth Odin, Staffan Nilsson, Göran Carlsson, Bengt Gustavsson
Molecular medicine - 2008 -
Colorectal carcinomas with microsatellite instability display increased thymidylate synthase gene expression
levels.
Elisabeth Odin, Yvonne Wettergren, Staffan Nilsson, Göran Carlsson, Bengt Gustavsson
Clinical Colorectal Cancer - 2007 -
Expression and clinical significance of methylenetetrahydrofolate reductase in patients with colorectal
cancer
Elisabeth Odin, Yvonne Wettergren, Göran Carlsson, Peter Danenberg, Angelo Termini, Roger Willen, Bengt Gustavsson
Clin Colorectal Cancer - 2006 -
Low expression of reduced folate carrier-1 and folylpolyglutamate synthase correlates with lack of a deleted in colorectal carcinoma mRNA splice variant in normal-appearing mucosa of colorectal carcinoma
patients
Yvonne Wettergren, Elisabeth Odin, Staffan Nilsson, Roger Willen, Göran Carlsson, Bengt Gustavsson
Cancer Detect Prev - 2005 -
Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer
patients.
Elisabeth Odin, Yvonne Wettergren, Staffan Nilsson, Roger Willén, Göran Carlsson, C Paul Spears, Lars Larsson, Bengt Gustavsson
Clinical cancer research : an official journal of the American Association for Cancer Research - 2003 -
Rapid method for relative gene expression determination in human tissues using automated capillary gel electrophoresis and multicolor
detection
Elisabeth Odin, Yvonne Wettergren, Lars Larsson, Per-Anders Larsson, Bengt Gustavsson
J Chromatogr B Biomed Sci Appl - 1999 -
Colcemid resistance in murine SEWA cells: non-Pgy gene amplification at low levels of resistance and preferential Pgy2 gene amplification at high levels of
resistance.
Yvonne Wettergren, A Kullberg, G Levan
Hereditas - 1995 -
C-band-positive double minutes have kinetochore
proteins.
Yvonne Wettergren, U Arnason, T Haaf, A Levan, G Levan
Cytogenetics and cell genetics - 1995 -
Drug-specific rearrangements of chromosome 12 in hydroxyurea-resistant mouse SEWA cells: support for chromosomal breakage model of gene
amplification.
Yvonne Wettergren, A Kullberg, G Levan
Somatic cell and molecular genetics - 1994 -
Amplification and overexpression of the mouse mdr 1a gene in nine independently derived multidrug-resistant SEWA murine cell
lines.
F Ståhl, Yvonne Wettergren, G Levan
Hereditas - 1993 -
Amplicon structure in multidrug-resistant murine cells: a nonrearranged region of genomic DNA corresponding to large circular
DNA.
F Ståhl, Yvonne Wettergren, G Levan
Molecular and cellular biology - 1992 -
Gene amplification in the murine SEWA
system.
G Levan, F Ståhl, Yvonne Wettergren
Mutation research - 1992 -
Chromatin bodies in multidrug resistant hybrid cells have centromeres and originate from homogeneously staining
regions.
A H Jakobsson, Yvonne Wettergren, T Haaf
Anticancer research - 1989 -
Isolation of selectively amplified DNA sequences from multidrug-resistant SEWA
cells.
F Stähl, P Sandberg, T Martinsson, J Skoog, B Dahllöf, Yvonne Wettergren, G Bjursell, G Levan
Hereditas - 1987 -
Pleiotropic drug resistance and gene amplification in a SEWA mouse tumor cell line. Complex relations revealed by drug uptake data, and lipid and protein
analysis.
Tommy Martinsson, B Dahllöf, Yvonne Wettergren, H Leffler, Göran Levan
Experimental cell research - 1985