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Malin Bäckström
Head of Unit
Core facilities-
The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based
cross-linking
Christian V Recktenwald, Göran Karlsson, Maria-Jose Garcia-Bonete, Gergely Katona, Maja Jensen, Richard Lymer, Malin Bäckström, Malin E V Johansson, Gunnar C. Hansson, Sergio Trillo-Muyo
Cell Reports - 2024 -
Serum IgG levels to Epstein-Barr and measles viruses in patients with multiple sclerosis during natalizumab and interferon beta
treatment
Linn Persson Berg, Marcus Eriksson, S. Longhi, I. Kockum, C. Warnke, Elisabeth Thomsson, Malin Bäckström, T. Olsson, A. Fogdell-Hahn, Tomas Bergström
Bmj Neurology Open - 2022 -
Sialic Acid and Fucose Residues on the SARS-CoV-2 Receptor-Binding Domain Modulate IgG Antibody
Reactivity
Ebba Samuelsson, Ekaterina Mirgorodskaya, Kristina Nyström, Malin Bäckström, Jan-Åke Liljeqvist, Rickard Nordén
Acs Infectious Diseases - 2022 -
A truncated glycoprotein G vaccine formulated with Advax-CpG adjuvant provides protection of mice against genital herpes simplex virus 2
infection
Staffan Görander, Y. Honda-Okubo, Malin Bäckström, J. Baldwin, Tomas Bergström, N. Petrovsky, Jan-Åke Liljeqvist
Vaccine - 2021 -
The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide
bonds
Erik Ehrencrona, Sjoerd van der Post, Pablo Gallego, Christian V Recktenwald, Ana Rodriguez-Piñeiro, Maria-Jose Garcia-Bonete, Sergio Trillo-Muyo, Malin Bäckström, Gunnar C. Hansson, Malin E V Johansson
Journal of Biological Chemistry - 2021 -
Recombinant Epstein-Barr virus glycoprotein 350 as a serological
antigen
Linn Persson Berg, Elisabeth Thomsson, Gentiana Hasi, Malin Bäckström, Tomas Bergström
Journal of Virological Methods - 2020 -
GM1 ganglioside-independent intoxication by Cholera
toxin
Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca E Riise, Malin Bäckström, Ville Wallenius, Frances M Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
PLoS Pathogens - 2018 -
GM1 ganglioside-independent intoxication by Cholera
toxin
Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca E Riise, Malin Bäckström, Ville Wallenius, Frances M Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
PLoS Pathogens - 2018 -
Intestinal MUC2 mucin supramolecular topology by packing and release resting on D3 domain
assembly.
Harriet E. Nilsson, Daniel Ambort, Malin Bäckström, Elisabeth Thomsson, Philip J B Koeck, Gunnar C. Hansson, Hans Hebert
Journal of molecular biology - 2014 -
Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease
(RgpB).
Sjoerd van der Post, Durai B Subramani, Malin Bäckström, Malin E V Johansson, Malene B Vester-Christensen, Ulla Mandel, Eric P Bennett, Henrik Clausen, Gunnar Dahlén, Aneta Sroka, Jan Potempa, Gunnar C. Hansson
The Journal of biological chemistry - 2013 -
Increased understanding of the biochemistry and biosynthesis of MUC2 and other gel-forming mucins through the recombinant expression of their protein
domains.
Malin Bäckström, Daniel Ambort, Elisabeth Thomsson, Malin E V Johansson, Gunnar C. Hansson
Molecular biotechnology - 2013 -
Composition and functional role of the mucus layers in the
intestine.
Malin E V Johansson, Daniel Ambort, Thaher Pelaseyed, André Schütte, Jenny K Gustafsson, Anna Ermund, Durai B Subramani, Jessica Holmén Larsson, Kristina A Thomsson, Joakim H. Bergström, Sjoerd van der Post, Ana María Rodríguez-Piñeiro, Henrik Sjövall, Malin Bäckström, Gunnar C. Hansson
Cellular and Molecular Life Sciences - 2011 -
Varicella-Zoster Virus (VZV) Glycoprotein E Is a Serological Antigen for Detection of Intrathecal Antibodies to VZV in Central Nervous System Infections, without Cross-Reaction to Herpes Simplex Virus
1
Anna Grahn, Marie Studahl, Staffan Nilsson, Elisabeth Thomsson, Malin Bäckström, Tomas Bergström
Clinical and Vaccine Immunology - 2011 -
Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for
varicella-zoster-virus-serology.
Elisabeth Thomsson, L. Persson, Ammi Grahn, Johanna Snäll, Maria Ekblad, Eva Brunhage, Frida Svensson, Gunnar C. Hansson, Malin Bäckström, Tomas Bergström
J. Virol. Methods - 2011 -
O-glycosylation of MUC1 mucin in prostate cancer and the effects of its expression on tumor growth in a prostate cancer xenograft
model.
Pushpa Premaratne, Karin Welén, Jan-Erik Damber, Gunnar C. Hansson, Malin Bäckström
Tumor Biol. - 2011 -
Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for varicella-zoster-virus
serology.
Elisabeth Thomsson, Linn Persson, Anna Grahn, Johanna Snäll, Maria Ekblad, Eva Brunhage, Frida Svensson, Christina Jern, Gunnar C. Hansson, Malin Bäckström, Tomas Bergström
Journal of virological methods - 2011 -
Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in
mice.
Judith Del Campo, Madelene Lindqvist, Maribel Cuello, Malin Bäckström, Osmir Cabrerra, Josefine Persson, Oliver Perez, Ali M Harandi
Vaccine - 2010 -
Comparison of methods for profiling O-glycosylation: Human Proteome Organisation Human Disease Glycomics/Proteome Initiative multi-institutional study of
IgA1.
Yoshinao Wada, Anne Dell, Stuart M Haslam, Bérangère Tissot, Kévin Canis, Parastoo Azadi, Malin Bäckström, Catherine E Costello, Gunnar C. Hansson, Yoshiyuki Hiki, Mayumi Ishihara, Hiromi Ito, Kazuaki Kakehi, Niclas G. Karlsson, C E Hayes, Koichi Kato, Nana Kawasaki, Kay-Hooi Khoo, Kunihiko Kobayashi, Daniel Kolarich, Akihiro Kondo, Carlito Lebrilla, Miyako Nakano, Hisashi Narimatsu, Jan Novak, Milos V Novotny, Erina Ohno, Nicolle H Packer, Elizabeth Palaima, Matthew B Renfrow, Michiko Tajiri, Kristina A Thomsson, Hirokazu Yagi, Shin-Yi Yu, Naoyuki Taniguchi
Molecular & cellular proteomics - 2010 -
Enhanced Detection of Sialylated and Sulfated Glycans with Negative Ion Mode Nanoliquid Chromatography/Mass Spectrometry at High
pH.
Kristina A Thomsson, Malin Bäckström, Jessica Holmén Larsson, Gunnar C. Hansson, Hasse Karlsson
Analytical chemistry - 2010 -
Decreased IgA antibody production in the stomach of gastric adenocarcinoma
patients.
Marianne Quiding-Järbrink, Patrik Sundström, Anna Lundgren, Malin Hansson, Malin Bäckström, Camilla Johansson, Karin Enarsson, Michael Hermansson, Erik Johnsson, Ann-Mari Svennerholm
Clinical immunology - 2009 -
Cervical mucins carry alpha(1,2)fucosylated glycans that partly protect from experimental vaginal
candidiasis.
Steven E Domino, Elizabeth A Hurd, Kristina A Thomsson, David M Karnak, Jessica Holmén Larsson, Elisabeth Thomsson, Malin Bäckström, Gunnar C. Hansson
Glycoconjugate journal - 2009 -
High-throughput and high-sensitivity nano-LC/MS and MS/MS for O-glycan
profiling.
Hasse Karlsson, Jessica Holmén Larsson, Kristina A Thomsson, Iris van Dijk Härd, Malin Bäckström, Gunnar C. Hansson
Methods in molecular biology (Clifton, N.J.) - 2009 -
Sensitive liquid chromatography-electrospray mass spectrometry allows for the analysis of the O-glycosylation of immunoprecipitated proteins from cells or tissues: application to MUC1 glycosylation in
cancer.
Malin Bäckström, Kristina A Thomsson, Hasse Karlsson, Gunnar C. Hansson
Journal of proteome research - 2009 -
Localization of O-glycans in MUC1 glycoproteins using electron-capture dissociation fragmentation mass
spectrometry.
Carina Sihlbom, Iris van Dijk Härd, Martin Lidell, Thomas Noll, Gunnar C. Hansson, Malin Bäckström
Glycobiology - 2009 -
Molecular evolution of specific human antibody against MUC1 mucin results in improved recognition of the antigen on tumor
cells.
Jonas Persson, Malin Bäckström, H Johansson, Karin Jirström, Gunnar C. Hansson, Mats Ohlin
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 2009 -
The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon
carcinoma
Eirikur Saeland, Sandra van Vliet, Malin Bäckström, Venice CM van den Berg, Teunis BH Geijtenbeek, Gerritt A Meijer, Yvette van Kooyk
Cancer Immunol Immunother - 2007 -
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in humna breast
cancer
Robert Sewell, Malin Bäckström, Martin Dalziel, Steven Gschmeissner, Hasse Karlsson, Thomas Noll, Jochem Gätgens, Henrik Clausen, Gunnar C. Hansson, J. Burchell, Joyce Taylor-Papadimitriou
J Biol Chem - 2006 -
A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4
transferase
Fredrik J. Olson, Malin Bäckström, Hasse Karlsson, J. Burchell, Gunnar C. Hansson
Glycobiology - 2005 -
Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic
cells
Aurelia Rughetti, Ilenia Pellicciotta, Mauro Biffoni, Malin Bäckström, Thomas Link, Eric P Bennet, Henrik Clausen, Gunnar C. Hansson, J. Burchell, Luigi Frati, Joyce Taylor-Papadimitriou, Marianna Nuti
J Immunol - 2005 -
Bioprocess development for the production of a recombinant MUC1 fusion protein expressed by CHO-K1 cells in protein-free
medium
Thomas Link, Malin Bäckström, Ros Graham, R Essers, K Zörner, Jochem Gätgens, J. Burchell, Joyce Taylor-Papadimitriou, Gunnar C. Hansson, Thomas Noll
J Biotechnol - 2004 -
Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary
cells.
Malin Bäckström, Thomas Link, Fredrik J. Olson, Hasse Karlsson, Rosalind Graham, Gianfranco Picco, Joy Burchell, Joyce Taylor-Papadimitriou, Thomas Noll, Gunnar C. Hansson
The Biochemical journal - 2003